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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
19.7
Human Site:
T304
Identified Species:
33.33
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
T304
Q
T
Y
E
L
N
E
T
A
K
Q
H
E
L
M
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
T304
Q
T
Y
E
L
N
E
T
A
K
Q
H
E
L
M
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
T300
Q
T
Y
E
L
N
E
T
A
K
Q
H
E
L
M
Dog
Lupus familis
XP_548052
697
79208
H256
D
M
D
Q
P
L
S
H
Y
F
I
S
S
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
T300
Q
T
Y
E
L
N
E
T
A
K
Q
H
E
L
M
Rat
Rattus norvegicus
P10688
756
85944
T263
E
R
Y
E
P
S
E
T
A
K
A
Q
R
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
N266
Y
L
L
S
A
D
G
N
V
F
N
L
A
H
K
Chicken
Gallus gallus
Q2VRL0
637
72514
I203
K
G
C
R
C
L
E
I
D
C
W
D
G
S
N
Frog
Xenopus laevis
Q32NH8
758
87399
T257
A
R
Y
E
P
S
D
T
A
K
K
L
H
A
M
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
W280
Q
T
F
E
L
N
D
W
A
Q
K
N
L
F
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
E286
N
D
Y
E
L
D
E
E
K
K
K
N
V
Q
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
E266
E
E
Y
E
P
N
Q
E
F
R
D
Q
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
V130
S
Y
L
T
G
N
Q
V
N
S
R
S
S
V
E
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Y347
D
R
Q
T
A
W
S
Y
F
I
K
Y
R
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
0
N.A.
100
46.6
N.A.
0
6.6
40
46.6
N.A.
40
N.A.
N.A.
20
P-Site Similarity:
100
100
100
6.6
N.A.
100
60
N.A.
6.6
13.3
60
80
N.A.
60
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
15
0
0
0
50
0
8
0
8
8
0
% A
% Cys:
0
0
8
0
8
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
15
8
8
0
0
15
15
0
8
0
8
8
0
0
0
% D
% Glu:
15
8
0
65
0
0
50
15
0
0
0
0
29
8
8
% E
% Phe:
0
0
8
0
0
0
0
0
15
15
0
0
0
8
0
% F
% Gly:
0
8
0
0
8
0
8
0
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
29
8
8
8
% H
% Ile:
0
0
0
0
0
0
0
8
0
8
8
0
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
0
8
50
29
0
8
0
8
% K
% Leu:
0
8
15
0
43
15
0
0
0
0
0
15
8
29
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
58
% M
% Asn:
8
0
0
0
0
50
0
8
8
0
8
15
0
0
8
% N
% Pro:
0
0
0
0
29
0
0
0
0
0
0
0
0
0
8
% P
% Gln:
36
0
8
8
0
0
15
0
0
8
29
15
0
15
0
% Q
% Arg:
0
22
0
8
0
0
0
0
0
8
8
0
15
0
0
% R
% Ser:
8
0
0
8
0
15
15
0
0
8
0
15
15
15
0
% S
% Thr:
0
36
0
15
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
8
8
0
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
8
0
8
0
0
8
0
0
0
0
% W
% Tyr:
8
8
58
0
0
0
0
8
8
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _