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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
17.88
Human Site:
T649
Identified Species:
30.26
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
T649
C
L
R
Q
P
D
S
T
F
D
P
E
Y
P
G
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
T648
C
L
R
Q
P
D
S
T
F
D
P
E
Y
P
G
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
T645
C
L
R
Q
P
D
S
T
F
D
P
E
D
P
G
Dog
Lupus familis
XP_548052
697
79208
P563
T
T
F
D
P
E
C
P
G
P
P
R
T
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
T645
Y
L
R
Q
L
N
T
T
F
D
P
E
C
P
G
Rat
Rattus norvegicus
P10688
756
85944
T614
F
L
R
D
P
N
T
T
F
N
S
R
A
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
R594
F
L
R
D
P
A
S
R
F
D
P
R
D
P
S
Chicken
Gallus gallus
Q2VRL0
637
72514
P510
N
V
G
R
Y
S
N
P
L
S
L
S
I
R
L
Frog
Xenopus laevis
Q32NH8
758
87399
T607
F
M
R
H
V
E
T
T
F
N
P
D
Q
P
Q
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
E630
P
K
S
D
F
D
P
E
N
T
G
G
G
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
D671
F
M
R
R
A
D
K
D
F
D
P
F
A
D
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
Q615
F
C
R
K
P
N
M
Q
F
N
P
L
K
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
G437
L
K
V
K
I
Y
T
G
E
G
W
D
L
D
F
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
I722
K
A
K
M
I
P
L
I
Y
E
H
F
E
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
93.3
13.3
N.A.
66.6
33.3
N.A.
53.3
0
33.3
20
N.A.
33.3
N.A.
N.A.
40
P-Site Similarity:
100
100
93.3
20
N.A.
80
53.3
N.A.
53.3
20
66.6
20
N.A.
46.6
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
8
8
0
0
0
0
0
0
15
0
8
% A
% Cys:
22
8
0
0
0
0
8
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
29
0
36
0
8
0
43
0
15
15
15
0
% D
% Glu:
0
0
0
0
0
15
0
8
8
8
0
29
8
0
0
% E
% Phe:
36
0
8
0
8
0
0
0
65
0
0
15
0
0
8
% F
% Gly:
0
0
8
0
0
0
0
8
8
8
8
8
8
0
50
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
0
8
0
0
0
0
8
0
0
% I
% Lys:
8
15
8
15
0
0
8
0
0
0
0
0
8
0
0
% K
% Leu:
8
43
0
0
8
0
8
0
8
0
8
8
8
8
15
% L
% Met:
0
15
0
8
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
22
8
0
8
22
0
0
0
8
0
% N
% Pro:
8
0
0
0
50
8
8
15
0
8
65
0
0
58
0
% P
% Gln:
0
0
0
29
0
0
0
8
0
0
0
0
8
0
8
% Q
% Arg:
0
0
65
15
0
0
0
8
0
0
0
22
0
8
0
% R
% Ser:
0
0
8
0
0
8
29
0
0
8
8
8
0
0
8
% S
% Thr:
8
8
0
0
0
0
29
43
0
8
0
0
8
8
8
% T
% Val:
0
8
8
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
0
8
8
0
0
8
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _