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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
19.7
Human Site:
Y190
Identified Species:
33.33
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
Y190
L
D
H
W
I
H
S
Y
L
H
R
A
D
S
N
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
Y190
L
D
H
W
I
H
S
Y
L
H
R
A
D
S
N
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
Y186
L
D
H
W
I
H
S
Y
L
H
R
A
D
S
N
Dog
Lupus familis
XP_548052
697
79208
P159
H
L
G
R
Q
L
Q
P
D
C
S
E
C
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
Y186
L
D
H
W
I
H
S
Y
L
H
R
A
D
S
D
Rat
Rattus norvegicus
P10688
756
85944
N161
K
N
K
D
N
K
M
N
F
K
E
L
K
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
F167
D
S
Y
A
R
W
I
F
K
E
C
D
K
S
N
Chicken
Gallus gallus
Q2VRL0
637
72514
E106
K
K
E
Q
F
K
T
E
G
A
E
T
T
A
L
Frog
Xenopus laevis
Q32NH8
758
87399
Q160
R
M
N
F
K
E
V
Q
D
L
L
K
M
M
N
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Y167
L
D
H
W
I
R
G
Y
L
R
R
A
D
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
S161
M
K
H
W
M
R
L
S
Y
C
V
E
K
S
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
K169
L
L
K
K
L
N
I
K
I
E
K
V
H
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
Y33
I
K
R
L
F
E
A
Y
S
R
N
G
K
M
S
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
V241
R
I
H
W
Q
I
T
V
S
E
K
E
E
D
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
0
N.A.
93.3
0
N.A.
13.3
0
6.6
73.3
N.A.
20
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
6.6
N.A.
26.6
13.3
20
73.3
N.A.
33.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
8
0
0
8
0
36
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
15
8
0
8
0
0
% C
% Asp:
8
36
0
8
0
0
0
0
15
0
0
8
36
22
8
% D
% Glu:
0
0
8
0
0
15
0
8
0
22
15
22
8
0
8
% E
% Phe:
0
0
0
8
15
0
0
8
8
0
0
0
0
0
8
% F
% Gly:
0
0
8
0
0
0
8
0
8
0
0
8
0
0
8
% G
% His:
8
0
50
0
0
29
0
0
0
29
0
0
8
0
8
% H
% Ile:
8
8
0
0
36
8
15
0
8
0
0
0
0
0
0
% I
% Lys:
15
22
15
8
8
15
0
8
8
8
15
8
29
0
8
% K
% Leu:
43
15
0
8
8
8
8
0
36
8
8
8
0
0
8
% L
% Met:
8
8
0
0
8
0
8
0
0
0
0
0
8
15
0
% M
% Asn:
0
8
8
0
8
8
0
8
0
0
8
0
0
0
43
% N
% Pro:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
15
0
8
8
0
0
0
0
0
8
0
% Q
% Arg:
15
0
8
8
8
15
0
0
0
15
36
0
0
0
0
% R
% Ser:
0
8
0
0
0
0
29
8
15
0
8
0
0
43
8
% S
% Thr:
0
0
0
0
0
0
15
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
0
8
8
0
0
8
8
0
0
0
% V
% Trp:
0
0
0
50
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
43
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _