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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCD3 All Species: 31.21
Human Site: Y370 Identified Species: 52.82
UniProt: Q8N3E9 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3E9 NP_588614.1 789 89258 Y370 G P S S T E A Y V R A F A Q G
Chimpanzee Pan troglodytes XP_001142960 788 88666 Y370 G P S S T E A Y V R A F A Q G
Rhesus Macaque Macaca mulatta XP_001115230 785 88822 Y366 G P S S T E A Y I R A F A Q G
Dog Lupus familis XP_548052 697 79208 V322 K I L F R D V V Q A V H D H A
Cat Felis silvestris
Mouse Mus musculus Q8K2J0 785 88588 Y366 G T S S T E A Y I R A F A Q G
Rat Rattus norvegicus P10688 756 85944 Y329 G P S S T E A Y I R A L C K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514368 738 83813 E332 C W D G S G N E P V I Y H G Y
Chicken Gallus gallus Q2VRL0 637 72514 I269 I A Q Y L L N I L G D K L L T
Frog Xenopus laevis Q32NH8 758 87399 Y323 G Q S S I E G Y I R A L K R G
Zebra Danio Brachydanio rerio A5D6R3 784 89362 Y346 S A S S T E P Y I R A L N Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P13217 1095 124845 Y352 G K S S V E M Y R Q T L L A G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001008790 753 85559 Y332 G P S S T E A Y I S A L Q R G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q56W08 564 64926 V196 F H V S D Y P V I I T L E D H
Baker's Yeast Sacchar. cerevisiae P32383 869 100529 Y413 E T P S V E G Y I Q V L Q Q G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.3 97.5 79.9 N.A. 88 49.1 N.A. 46.7 26.7 48.5 52.3 N.A. 24.1 N.A. N.A. 37.3
Protein Similarity: 100 96.6 98.2 83 N.A. 92.2 66.1 N.A. 62 44.8 65.9 69.8 N.A. 38.2 N.A. N.A. 57.1
P-Site Identity: 100 100 93.3 0 N.A. 86.6 73.3 N.A. 0 0 53.3 60 N.A. 40 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 6.6 N.A. 93.3 86.6 N.A. 13.3 6.6 66.6 66.6 N.A. 46.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 23.7 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. 37.9 43.1 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 15 0 0 0 0 43 0 0 8 58 0 29 8 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 0 8 8 0 0 0 0 8 0 8 8 0 % D
% Glu: 8 0 0 0 0 72 0 8 0 0 0 0 8 0 0 % E
% Phe: 8 0 0 8 0 0 0 0 0 0 0 29 0 0 0 % F
% Gly: 58 0 0 8 0 8 15 0 0 8 0 0 0 8 72 % G
% His: 0 8 0 0 0 0 0 0 0 0 0 8 8 8 8 % H
% Ile: 8 8 0 0 8 0 0 8 58 8 8 0 0 0 0 % I
% Lys: 8 8 0 0 0 0 0 0 0 0 0 8 8 8 0 % K
% Leu: 0 0 8 0 8 8 0 0 8 0 0 50 15 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 15 0 0 0 0 0 8 0 0 % N
% Pro: 0 36 8 0 0 0 15 0 8 0 0 0 0 0 0 % P
% Gln: 0 8 8 0 0 0 0 0 8 15 0 0 15 43 0 % Q
% Arg: 0 0 0 0 8 0 0 0 8 50 0 0 0 15 0 % R
% Ser: 8 0 65 79 8 0 0 0 0 8 0 0 0 0 0 % S
% Thr: 0 15 0 0 50 0 0 0 0 0 15 0 0 0 8 % T
% Val: 0 0 8 0 15 0 8 15 15 8 15 0 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 0 72 0 0 0 8 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _