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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
31.82
Human Site:
Y586
Identified Species:
53.85
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
Y586
A
R
Q
L
T
R
V
Y
P
L
G
L
R
M
N
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
S586
A
L
C
R
E
E
C
S
P
L
K
L
S
S
E
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
Y582
A
R
Q
L
T
R
V
Y
P
L
G
L
R
M
N
Dog
Lupus familis
XP_548052
697
79208
S502
P
L
G
L
R
M
N
S
A
N
Y
S
P
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
Y582
T
Q
Q
L
T
R
V
Y
P
L
G
L
R
M
N
Rat
Rattus norvegicus
P10688
756
85944
Y551
V
S
C
L
S
R
I
Y
P
A
G
W
R
T
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
Y531
A
K
Y
L
S
R
I
Y
P
A
G
R
R
T
D
Chicken
Gallus gallus
Q2VRL0
637
72514
Q449
G
S
S
N
Y
N
P
Q
E
F
W
N
V
G
C
Frog
Xenopus laevis
Q32NH8
758
87399
Y544
A
W
Q
L
M
R
I
Y
P
T
G
L
R
T
D
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Y563
S
R
Q
L
S
R
I
Y
P
S
A
Q
R
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
Y608
K
R
Q
M
S
R
I
Y
P
K
G
T
R
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
Y552
K
I
F
L
S
R
I
Y
P
G
G
L
R
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
Q376
V
G
W
T
H
G
A
Q
M
V
A
F
N
M
Q
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
Y645
R
R
Y
L
M
R
V
Y
P
H
V
L
R
Y
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
26.6
100
6.6
N.A.
86.6
40
N.A.
46.6
0
60
46.6
N.A.
46.6
N.A.
N.A.
53.3
P-Site Similarity:
100
26.6
100
6.6
N.A.
93.3
60
N.A.
73.3
0
73.3
73.3
N.A.
73.3
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
36
0
0
0
0
0
8
0
8
15
15
0
0
8
0
% A
% Cys:
0
0
15
0
0
0
8
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% D
% Glu:
0
0
0
0
8
8
0
0
8
0
0
0
0
0
15
% E
% Phe:
0
0
8
0
0
0
0
0
0
8
0
8
0
0
0
% F
% Gly:
8
8
8
0
0
8
0
0
0
8
58
0
0
8
0
% G
% His:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
43
0
0
0
0
0
0
0
0
% I
% Lys:
15
8
0
0
0
0
0
0
0
8
8
0
0
0
8
% K
% Leu:
0
15
0
72
0
0
0
0
0
29
0
50
0
8
0
% L
% Met:
0
0
0
8
15
8
0
0
8
0
0
0
0
29
0
% M
% Asn:
0
0
0
8
0
8
8
0
0
8
0
8
8
0
29
% N
% Pro:
8
0
0
0
0
0
8
0
79
0
0
0
8
0
0
% P
% Gln:
0
8
43
0
0
0
0
15
0
0
0
8
0
8
15
% Q
% Arg:
8
36
0
8
8
72
0
0
0
0
0
8
72
0
0
% R
% Ser:
8
15
8
0
36
0
0
15
0
8
0
8
8
8
0
% S
% Thr:
8
0
0
8
22
0
0
0
0
8
0
8
0
29
0
% T
% Val:
15
0
0
0
0
0
29
0
0
8
8
0
8
0
0
% V
% Trp:
0
8
8
0
0
0
0
0
0
0
8
8
0
0
0
% W
% Tyr:
0
0
15
0
8
0
0
72
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _