KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCD3
All Species:
34.85
Human Site:
Y739
Identified Species:
58.97
UniProt:
Q8N3E9
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3E9
NP_588614.1
789
89258
Y739
V
R
F
V
V
E
D
Y
D
A
T
S
P
N
D
Chimpanzee
Pan troglodytes
XP_001142960
788
88666
Y738
V
R
F
V
V
E
D
Y
D
A
T
S
P
N
D
Rhesus Macaque
Macaca mulatta
XP_001115230
785
88822
Y735
V
R
F
V
V
E
D
Y
D
A
T
S
P
N
D
Dog
Lupus familis
XP_548052
697
79208
Y647
V
R
F
V
V
E
D
Y
D
T
T
S
P
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2J0
785
88588
Y735
V
R
F
V
V
E
D
Y
D
T
T
S
P
N
D
Rat
Rattus norvegicus
P10688
756
85944
Y707
V
R
F
M
V
E
D
Y
D
S
S
S
K
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514368
738
83813
Y688
V
R
F
V
V
D
D
Y
D
I
S
S
K
N
D
Chicken
Gallus gallus
Q2VRL0
637
72514
D588
L
I
R
F
C
V
Q
D
E
I
S
L
V
A
N
Frog
Xenopus laevis
Q32NH8
758
87399
Y701
V
R
F
V
V
E
D
Y
D
K
T
S
R
N
D
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
H720
V
R
F
M
V
E
D
H
D
H
K
S
K
N
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13217
1095
124845
G758
D
L
A
V
L
R
F
G
V
Y
E
E
S
G
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001008790
753
85559
Y703
I
R
L
V
V
Q
D
Y
D
M
A
S
S
N
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q56W08
564
64926
Q515
Q
D
Y
D
N
D
T
Q
N
D
F
A
G
Q
T
Baker's Yeast
Sacchar. cerevisiae
P32383
869
100529
T814
V
S
I
T
L
K
D
T
D
L
T
F
I
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
97.5
79.9
N.A.
88
49.1
N.A.
46.7
26.7
48.5
52.3
N.A.
24.1
N.A.
N.A.
37.3
Protein Similarity:
100
96.6
98.2
83
N.A.
92.2
66.1
N.A.
62
44.8
65.9
69.8
N.A.
38.2
N.A.
N.A.
57.1
P-Site Identity:
100
100
100
93.3
N.A.
93.3
73.3
N.A.
73.3
0
86.6
66.6
N.A.
6.6
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
26.6
86.6
80
N.A.
13.3
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.7
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37.9
43.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
22
8
8
0
8
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
8
0
15
79
8
79
8
0
0
0
0
65
% D
% Glu:
0
0
0
0
0
58
0
0
8
0
8
8
0
0
8
% E
% Phe:
0
0
65
8
0
0
8
0
0
0
8
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
8
8
8
0
0
0
0
0
0
15
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
8
0
22
8
8
% K
% Leu:
8
8
8
0
15
0
0
0
0
8
0
8
0
0
0
% L
% Met:
0
0
0
15
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
0
0
72
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
36
0
0
% P
% Gln:
8
0
0
0
0
8
8
8
0
0
0
0
0
8
0
% Q
% Arg:
0
72
8
0
0
8
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
8
0
0
0
0
0
0
0
8
22
72
15
0
0
% S
% Thr:
0
0
0
8
0
0
8
8
0
15
50
0
0
0
8
% T
% Val:
72
0
0
65
72
8
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
65
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _