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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPM1K All Species: 29.09
Human Site: S48 Identified Species: 58.18
UniProt: Q8N3J5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3J5 NP_689755.3 372 40997 S48 S T S E P R C S R F D P D G S
Chimpanzee Pan troglodytes XP_517334 352 38770 S48 S T S E P R C S R F D P D G S
Rhesus Macaque Macaca mulatta XP_001099949 372 40959 S48 S T S E P R C S R F D P D G S
Dog Lupus familis XP_535651 372 40939 S48 S T S E P R C S R F D P D G S
Cat Felis silvestris
Mouse Mus musculus Q8BXN7 372 40900 S48 S T S E A R C S R F D P D G S
Rat Rattus norvegicus NP_001101333 372 40995 S48 S I S E P R C S R F D P D G S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_420574 580 63208 S256 S T S E R R A S R F D P D G S
Frog Xenopus laevis Q6ING9 373 41518 S49 A N R R C F S S R F D L D G S
Zebra Danio Brachydanio rerio XP_690577 358 39875 F50 R P A T W D S F G I W D N R I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795565 442 49423 T119 W R R S L N T T S S R C S S S
Poplar Tree Populus trichocarpa XP_002308720 292 31307
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35182 281 31531
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.7 99.1 95.4 N.A. 90.3 90.5 N.A. N.A. 53.6 72.1 61.2 N.A. N.A. N.A. N.A. 41.1
Protein Similarity: 100 90.8 99.7 97.5 N.A. 95.1 94.8 N.A. N.A. 58.9 82.8 75 N.A. N.A. N.A. N.A. 55.6
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 46.6 0 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. N.A. 86.6 53.3 13.3 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: 26.8 N.A. N.A. N.A. 22.5 N.A.
Protein Similarity: 45.7 N.A. N.A. N.A. 38.7 N.A.
P-Site Identity: 0 N.A. N.A. N.A. 0 N.A.
P-Site Similarity: 0 N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 9 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 9 0 50 0 0 0 0 9 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 0 0 0 67 9 67 0 0 % D
% Glu: 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 9 0 9 0 67 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 9 0 0 0 0 67 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 0 0 9 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 9 0 0 42 0 0 0 0 0 0 59 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 9 9 17 9 9 59 0 0 67 0 9 0 0 9 0 % R
% Ser: 59 0 59 9 0 0 17 67 9 9 0 0 9 9 75 % S
% Thr: 0 50 0 9 0 0 9 9 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 9 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _