KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPM1K
All Species:
24.24
Human Site:
T35
Identified Species:
48.48
UniProt:
Q8N3J5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3J5
NP_689755.3
372
40997
T35
L
Q
D
D
R
R
V
T
P
T
C
H
S
S
T
Chimpanzee
Pan troglodytes
XP_517334
352
38770
T35
L
Q
D
D
R
R
V
T
P
T
C
H
S
S
T
Rhesus Macaque
Macaca mulatta
XP_001099949
372
40959
T35
L
Q
D
D
R
R
V
T
P
T
C
H
S
S
T
Dog
Lupus familis
XP_535651
372
40939
T35
L
Q
D
D
R
R
L
T
P
T
C
H
G
S
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXN7
372
40900
T35
L
Q
D
H
R
Q
A
T
P
A
C
Y
F
S
T
Rat
Rattus norvegicus
NP_001101333
372
40995
T35
L
Q
D
H
R
Q
M
T
P
A
C
Y
C
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_420574
580
63208
T243
L
Q
D
E
K
R
T
T
A
E
C
C
I
S
T
Frog
Xenopus laevis
Q6ING9
373
41518
T36
E
H
S
C
T
T
S
T
R
H
C
F
S
A
N
Zebra Danio
Brachydanio rerio
XP_690577
358
39875
D37
R
W
H
T
T
R
L
D
M
D
G
S
G
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795565
442
49423
P106
T
P
Q
S
E
I
I
P
Q
I
S
H
R
W
R
Poplar Tree
Populus trichocarpa
XP_002308720
292
31307
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35182
281
31531
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.7
99.1
95.4
N.A.
90.3
90.5
N.A.
N.A.
53.6
72.1
61.2
N.A.
N.A.
N.A.
N.A.
41.1
Protein Similarity:
100
90.8
99.7
97.5
N.A.
95.1
94.8
N.A.
N.A.
58.9
82.8
75
N.A.
N.A.
N.A.
N.A.
55.6
P-Site Identity:
100
100
100
86.6
N.A.
60
53.3
N.A.
N.A.
53.3
20
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
N.A.
66.6
26.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
26.8
N.A.
N.A.
N.A.
22.5
N.A.
Protein Similarity:
45.7
N.A.
N.A.
N.A.
38.7
N.A.
P-Site Identity:
0
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
0
N.A.
N.A.
N.A.
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
9
17
0
0
0
9
0
% A
% Cys:
0
0
0
9
0
0
0
0
0
0
67
9
9
0
0
% C
% Asp:
0
0
59
34
0
0
0
9
0
9
0
0
0
0
0
% D
% Glu:
9
0
0
9
9
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
17
0
0
% G
% His:
0
9
9
17
0
0
0
0
0
9
0
42
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
0
0
9
0
0
9
0
9
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
59
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
9
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
0
0
0
0
0
9
50
0
0
0
0
0
9
% P
% Gln:
0
59
9
0
0
17
0
0
9
0
0
0
0
0
0
% Q
% Arg:
9
0
0
0
50
50
0
0
9
0
0
0
9
9
9
% R
% Ser:
0
0
9
9
0
0
9
0
0
0
9
9
34
59
0
% S
% Thr:
9
0
0
9
17
9
9
67
0
34
0
0
0
0
50
% T
% Val:
0
0
0
0
0
0
25
0
0
0
0
0
0
0
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _