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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TXLNB All Species: 18.18
Human Site: S554 Identified Species: 40
UniProt: Q8N3L3 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3L3 NP_694967.3 684 76519 S554 I P S R D S E S P L P P L T P
Chimpanzee Pan troglodytes XP_518873 787 88160 S657 I P S P D S E S P L P P L T P
Rhesus Macaque Macaca mulatta XP_001096391 763 85606 S633 I P S R D S E S P L P P L T P
Dog Lupus familis XP_533429 694 77425 S562 G P L C H S E S S L P P L T P
Cat Felis silvestris
Mouse Mus musculus Q8VBT1 685 77188 S558 H P S L P A D S G S P R P P V
Rat Rattus norvegicus NP_001129331 690 77524 S563 H P N P S S V S G S P Q P P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508877 1096 121013 L746 Q P G Q P K A L A Q G Q P G Q
Chicken Gallus gallus Q9I969 676 77002 N551 T S Q P E A G N H C E Q F S M
Frog Xenopus laevis NP_001090396 513 59025 E399 K I K K L E K E T T M Y R S R
Zebra Danio Brachydanio rerio XP_691474 798 90692 S554 K S T Q D E S S T I K V T I T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780699 544 61541 S430 R W E T S N K S L M T M V E E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.3 85.4 79.9 N.A. 72.2 72.1 N.A. 43.4 55.1 41.8 44.4 N.A. N.A. N.A. N.A. 36.2
Protein Similarity: 100 85.7 87.1 83.4 N.A. 79.4 78.4 N.A. 50.7 66.5 53.7 59.5 N.A. N.A. N.A. N.A. 50.8
P-Site Identity: 100 93.3 100 66.6 N.A. 26.6 26.6 N.A. 6.6 0 0 13.3 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 93.3 100 66.6 N.A. 40 33.3 N.A. 13.3 26.6 20 33.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 19 10 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 37 0 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 0 10 19 37 10 0 0 10 0 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 10 0 10 0 0 0 10 0 19 0 10 0 0 10 0 % G
% His: 19 0 0 0 10 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 28 10 0 0 0 0 0 0 0 10 0 0 0 10 0 % I
% Lys: 19 0 10 10 0 10 19 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 10 10 10 0 0 10 10 37 0 0 37 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 10 10 0 0 10 % M
% Asn: 0 0 10 0 0 10 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 64 0 28 19 0 0 0 28 0 55 37 28 19 37 % P
% Gln: 10 0 10 19 0 0 0 0 0 10 0 28 0 0 10 % Q
% Arg: 10 0 0 19 0 0 0 0 0 0 0 10 10 0 10 % R
% Ser: 0 19 37 0 19 46 10 73 10 19 0 0 0 19 0 % S
% Thr: 10 0 10 10 0 0 0 0 19 10 10 0 10 37 10 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 10 10 0 19 % V
% Trp: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _