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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VPS8 All Species: 16.36
Human Site: S1157 Identified Species: 45
UniProt: Q8N3P4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3P4 NP_001009921.1 1428 161740 S1157 M M A P Q K L S S S A I P H L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001097221 1428 161709 S1157 M M A P Q K L S S S A I P H L
Dog Lupus familis XP_849791 1428 161644 S1157 M M A P Q K L S G S A A P H L
Cat Felis silvestris
Mouse Mus musculus Q0P5W1 1427 161127 S1156 M T P Q K L S S S A A A P H P
Rat Rattus norvegicus XP_221315 1430 161513 S1159 A P Q K L S S S A A A P P H P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_426694 1588 178082 S1315 M M S P Q K L S G S S H P L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_648048 1229 137903 R968 S T V E E F L R S N S G Y R L
Honey Bee Apis mellifera XP_393123 1184 130762 E923 K A N H K D A E A V M L E K L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798078 1375 154122 E1108 K L D E E G R E T L W F P L L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.9 97.3 N.A. 93.4 93.7 N.A. N.A. 74.5 N.A. N.A. N.A. 31.2 33.4 N.A. 48
Protein Similarity: 100 N.A. 99.7 98.5 N.A. 96.3 96.1 N.A. N.A. 81.8 N.A. N.A. N.A. 52.9 52.6 N.A. 68.5
P-Site Identity: 100 N.A. 100 86.6 N.A. 40 26.6 N.A. N.A. 66.6 N.A. N.A. N.A. 20 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. 100 86.6 N.A. 53.3 40 N.A. N.A. 80 N.A. N.A. N.A. 40 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 12 34 0 0 0 12 0 23 23 56 23 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 12 0 0 12 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 23 23 0 0 23 0 0 0 0 12 0 0 % E
% Phe: 0 0 0 0 0 12 0 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 0 0 12 0 0 23 0 0 12 0 0 0 % G
% His: 0 0 0 12 0 0 0 0 0 0 0 12 0 56 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 23 0 0 0 % I
% Lys: 23 0 0 12 23 45 0 0 0 0 0 0 0 12 0 % K
% Leu: 0 12 0 0 12 12 56 0 0 12 0 12 0 23 78 % L
% Met: 56 45 0 0 0 0 0 0 0 0 12 0 0 0 0 % M
% Asn: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % N
% Pro: 0 12 12 45 0 0 0 0 0 0 0 12 78 0 23 % P
% Gln: 0 0 12 12 45 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 12 12 0 0 0 0 0 12 0 % R
% Ser: 12 0 12 0 0 12 23 67 45 45 23 0 0 0 0 % S
% Thr: 0 23 0 0 0 0 0 0 12 0 0 0 0 0 0 % T
% Val: 0 0 12 0 0 0 0 0 0 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 12 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 12 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _