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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS8
All Species:
25.76
Human Site:
S387
Identified Species:
70.83
UniProt:
Q8N3P4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3P4
NP_001009921.1
1428
161740
S387
L
L
V
K
R
D
E
S
G
A
I
H
V
T
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001097221
1428
161709
S387
L
L
V
K
R
D
E
S
G
A
I
H
V
T
K
Dog
Lupus familis
XP_849791
1428
161644
S387
L
L
V
K
R
D
E
S
G
A
I
H
V
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q0P5W1
1427
161127
S385
L
L
V
K
R
D
E
S
G
A
I
H
V
T
K
Rat
Rattus norvegicus
XP_221315
1430
161513
S387
L
L
V
K
R
D
E
S
G
A
I
H
V
T
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426694
1588
178082
T547
L
L
V
K
R
D
D
T
G
A
I
H
V
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648048
1229
137903
Y275
G
R
H
E
L
D
Q
Y
C
I
V
A
L
A
T
Honey Bee
Apis mellifera
XP_393123
1184
130762
D230
P
K
V
A
L
C
S
D
S
G
G
S
V
F
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798078
1375
154122
S362
P
L
Q
S
I
I
L
S
Y
S
L
L
N
V
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.9
97.3
N.A.
93.4
93.7
N.A.
N.A.
74.5
N.A.
N.A.
N.A.
31.2
33.4
N.A.
48
Protein Similarity:
100
N.A.
99.7
98.5
N.A.
96.3
96.1
N.A.
N.A.
81.8
N.A.
N.A.
N.A.
52.9
52.6
N.A.
68.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
86.6
N.A.
N.A.
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
N.A.
N.A.
33.3
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
0
0
0
67
0
12
0
12
0
% A
% Cys:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
78
12
12
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
12
0
0
56
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% F
% Gly:
12
0
0
0
0
0
0
0
67
12
12
0
0
0
0
% G
% His:
0
0
12
0
0
0
0
0
0
0
0
67
0
0
0
% H
% Ile:
0
0
0
0
12
12
0
0
0
12
67
0
0
0
0
% I
% Lys:
0
12
0
67
0
0
0
0
0
0
0
0
0
0
67
% K
% Leu:
67
78
0
0
23
0
12
0
0
0
12
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% N
% Pro:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
12
0
0
0
0
0
0
0
12
% Q
% Arg:
0
12
0
0
67
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
0
0
12
67
12
12
0
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
67
12
% T
% Val:
0
0
78
0
0
0
0
0
0
0
12
0
78
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
12
12
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _