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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPP5 All Species: 28.48
Human Site: Y243 Identified Species: 44.76
UniProt: Q8N3R9 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3R9 NP_071919.2 675 77294 Y243 P I T D E R V Y E S I G Q Y G
Chimpanzee Pan troglodytes XP_510014 764 85553 Y332 P I T D E R V Y E S I G Q Y G
Rhesus Macaque Macaca mulatta XP_001105724 674 77301 Y242 P I T D E R V Y E S I G Q Y G
Dog Lupus familis XP_547862 675 77214 Y243 P F T D E R V Y E S I G Q Y G
Cat Felis silvestris
Mouse Mus musculus Q9JLB2 675 77211 Y243 P I T D E R V Y E S I G H Y G
Rat Rattus norvegicus Q5U2Y3 576 65604 S208 I I Q I L S Q S Q G A I T F K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505475 675 76860 Y243 S L T D E R V Y E S V G Q Y G
Chicken Gallus gallus Q5ZJ00 468 52501 H103 C M V A R I F H G G M I H R Q
Frog Xenopus laevis NP_001085267 675 76810 Y243 P S S E D C F Y E N I G L Y G
Zebra Danio Brachydanio rerio Q8JHF4 677 76390 S245 L V P S V N A S E T L T Q W G
Tiger Blowfish Takifugu rubipres P49697 467 52590 L102 R C S V A R I L H G G M I H R
Fruit Fly Dros. melanogaster Q24210 898 100893 L479 P Y L N G D E L D N V E G G E
Honey Bee Apis mellifera XP_393395 1033 115664 S582 S G P P S P T S S W R G S R V
Nematode Worm Caenorhab. elegans P54936 961 108794 V423 A L P C E P V V T E V D T S T
Sea Urchin Strong. purpuratus XP_784409 971 107892 D538 L P T D V Y Q D I D L P E D G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86.6 97 98.2 N.A. 96.7 36.2 N.A. 93.7 25 86 77 25.7 26.7 34.7 24.1 34.7
Protein Similarity: 100 87.5 97.7 99.5 N.A. 98.6 54.9 N.A. 96.8 43.8 92.5 86.7 44.5 46.3 49.2 41.7 49.2
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 80 0 46.6 20 6.6 6.6 6.6 13.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 20 N.A. 93.3 20 73.3 46.6 26.6 33.3 6.6 26.6 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 0 7 7 0 7 0 0 0 7 0 0 0 0 % A
% Cys: 7 7 0 7 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 47 7 7 0 7 7 7 0 7 0 7 0 % D
% Glu: 0 0 0 7 47 0 7 0 54 7 0 7 7 0 7 % E
% Phe: 0 7 0 0 0 0 14 0 0 0 0 0 0 7 0 % F
% Gly: 0 7 0 0 7 0 0 0 7 20 7 54 7 7 60 % G
% His: 0 0 0 0 0 0 0 7 7 0 0 0 14 7 0 % H
% Ile: 7 34 0 7 0 7 7 0 7 0 40 14 7 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 14 14 7 0 7 0 0 14 0 0 14 0 7 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 0 7 7 0 0 0 % M
% Asn: 0 0 0 7 0 7 0 0 0 14 0 0 0 0 0 % N
% Pro: 47 7 20 7 0 14 0 0 0 0 0 7 0 0 0 % P
% Gln: 0 0 7 0 0 0 14 0 7 0 0 0 40 0 7 % Q
% Arg: 7 0 0 0 7 47 0 0 0 0 7 0 0 14 7 % R
% Ser: 14 7 14 7 7 7 0 20 7 40 0 0 7 7 0 % S
% Thr: 0 0 47 0 0 0 7 0 7 7 0 7 14 0 7 % T
% Val: 0 7 7 7 14 0 47 7 0 0 20 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 7 0 0 0 7 0 % W
% Tyr: 0 7 0 0 0 7 0 47 0 0 0 0 0 47 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _