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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPP5
All Species:
38.18
Human Site:
Y652
Identified Species:
60
UniProt:
Q8N3R9
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3R9
NP_071919.2
675
77294
Y652
N
S
D
L
D
K
A
Y
Q
E
L
L
R
L
I
Chimpanzee
Pan troglodytes
XP_510014
764
85553
Y741
N
S
D
L
D
K
A
Y
Q
E
L
L
R
L
I
Rhesus Macaque
Macaca mulatta
XP_001105724
674
77301
Y651
N
S
D
L
D
K
A
Y
Q
E
L
L
R
L
I
Dog
Lupus familis
XP_547862
675
77214
Y652
N
S
D
L
D
K
A
Y
Q
E
L
L
R
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLB2
675
77211
Y652
N
S
D
L
D
K
A
Y
Q
E
L
L
R
L
I
Rat
Rattus norvegicus
Q5U2Y3
576
65604
F552
N
D
D
L
T
V
A
F
N
E
L
K
T
T
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505475
675
76860
Y652
N
S
D
L
N
K
A
Y
Q
E
L
L
R
L
I
Chicken
Gallus gallus
Q5ZJ00
468
52501
K446
N
G
V
E
E
S
L
K
L
L
E
E
A
F
E
Frog
Xenopus laevis
NP_001085267
675
76810
Y652
N
T
D
L
D
K
A
Y
Q
E
L
I
R
L
I
Zebra Danio
Brachydanio rerio
Q8JHF4
677
76390
Y654
N
T
D
L
D
K
S
Y
Q
E
L
L
R
L
I
Tiger Blowfish
Takifugu rubipres
P49697
467
52590
K445
N
D
V
N
E
S
V
K
I
V
E
E
A
L
E
Fruit Fly
Dros. melanogaster
Q24210
898
100893
I875
N
N
D
I
S
E
T
I
A
T
L
E
T
A
I
Honey Bee
Apis mellifera
XP_393395
1033
115664
Y1010
N
T
D
T
D
R
A
Y
N
Q
L
L
T
E
I
Nematode Worm
Caenorhab. elegans
P54936
961
108794
I938
N
S
D
I
D
D
T
I
A
Q
L
E
R
L
V
Sea Urchin
Strong. purpuratus
XP_784409
971
107892
Y948
H
H
D
H
D
R
A
Y
N
D
L
I
S
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.6
97
98.2
N.A.
96.7
36.2
N.A.
93.7
25
86
77
25.7
26.7
34.7
24.1
34.7
Protein Similarity:
100
87.5
97.7
99.5
N.A.
98.6
54.9
N.A.
96.8
43.8
92.5
86.7
44.5
46.3
49.2
41.7
49.2
P-Site Identity:
100
100
100
100
N.A.
100
40
N.A.
93.3
6.6
86.6
86.6
13.3
26.6
53.3
46.6
40
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
100
13.3
100
100
20
46.6
73.3
66.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
67
0
14
0
0
0
14
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
14
87
0
67
7
0
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
0
7
14
7
0
0
0
60
14
27
0
14
14
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
7
% F
% Gly:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
14
0
0
0
14
7
0
0
14
0
0
74
% I
% Lys:
0
0
0
0
0
54
0
14
0
0
0
7
0
0
0
% K
% Leu:
0
0
0
60
0
0
7
0
7
7
87
54
0
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
94
7
0
7
7
0
0
0
20
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
54
14
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
14
0
0
0
0
0
0
60
0
0
% R
% Ser:
0
47
0
0
7
14
7
0
0
0
0
0
7
0
0
% S
% Thr:
0
20
0
7
7
0
14
0
0
7
0
0
20
7
0
% T
% Val:
0
0
14
0
0
7
7
0
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _