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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYNPO All Species: 8.48
Human Site: T483 Identified Species: 26.67
UniProt: Q8N3V7 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N3V7 NP_001103444.1 929 99463 T483 P P S V V N R T A R P F G I Q
Chimpanzee Pan troglodytes XP_527075 1310 140528 T650 P P S V V N R T A R P F G I Q
Rhesus Macaque Macaca mulatta XP_001099989 1010 108015 T514 D L L D L V Q T A D E K R R Q
Dog Lupus familis XP_536465 891 96106 E462 P G S T S Q M E R S P M V E R
Cat Felis silvestris
Mouse Mus musculus Q8CC35 929 99533 G481 P F G I Q S P G T S Q I E Q S
Rat Rattus norvegicus Q9Z327 931 99967 F476 V N R T A R P F G M Q S P G T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509564 896 96611 S468 H S V V M A A S T P M G E R T
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001339344 659 72710 T231 Q C N G K S T T T K Q Q T I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 70.1 77.3 74.4 N.A. 79.5 79.4 N.A. 48.1 N.A. N.A. 30.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 70.3 77.8 79.6 N.A. 84.5 85 N.A. 60.9 N.A. N.A. 41.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 20 20 N.A. 6.6 0 N.A. 6.6 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 26.6 N.A. 20 0 N.A. 20 N.A. N.A. 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 13 13 13 0 38 0 0 0 0 0 0 % A
% Cys: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 13 0 0 0 0 0 13 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 13 0 0 13 0 25 13 0 % E
% Phe: 0 13 0 0 0 0 0 13 0 0 0 25 0 0 0 % F
% Gly: 0 13 13 13 0 0 0 13 13 0 0 13 25 13 0 % G
% His: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 13 0 0 0 0 0 0 0 13 0 38 0 % I
% Lys: 0 0 0 0 13 0 0 0 0 13 0 13 0 0 0 % K
% Leu: 0 13 13 0 13 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 13 0 13 0 0 13 13 13 0 0 0 % M
% Asn: 0 13 13 0 0 25 0 0 0 0 0 0 0 0 0 % N
% Pro: 50 25 0 0 0 0 25 0 0 13 38 0 13 0 0 % P
% Gln: 13 0 0 0 13 13 13 0 0 0 38 13 0 13 38 % Q
% Arg: 0 0 13 0 0 13 25 0 13 25 0 0 13 25 13 % R
% Ser: 0 13 38 0 13 25 0 13 0 25 0 13 0 0 13 % S
% Thr: 0 0 0 25 0 0 13 50 38 0 0 0 13 0 25 % T
% Val: 13 0 13 38 25 13 0 0 0 0 0 0 13 0 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _