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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRSS35
All Species:
15.76
Human Site:
Y277
Identified Species:
43.33
UniProt:
Q8N3Z0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z0
NP_699193.1
413
47098
Y277
D
A
T
L
D
Y
D
Y
A
L
L
E
L
K
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q1WK24
409
46494
Y273
D
A
A
L
D
Y
D
Y
A
L
L
E
L
K
R
Dog
Lupus familis
XP_539023
357
40123
K227
D
Y
A
L
L
E
L
K
R
A
H
K
K
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8C0F9
409
45768
L275
A
L
D
Y
D
Y
A
L
L
E
L
K
R
A
H
Rat
Rattus norvegicus
Q5R212
406
45477
L272
A
L
D
F
D
Y
A
L
L
E
L
K
R
A
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512903
412
47052
Y276
D
V
V
L
D
Y
D
Y
A
V
L
E
L
K
R
Chicken
Gallus gallus
XP_419860
413
46849
Y277
D
V
A
L
D
Y
D
Y
A
V
L
E
L
K
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001002212
418
47252
Y282
N
V
L
A
D
Y
D
Y
A
V
L
E
L
K
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796599
311
35578
L181
K
D
Y
A
V
L
S
L
K
R
S
P
D
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.6
78.9
N.A.
77.2
78.6
N.A.
73.6
70.2
N.A.
52.6
N.A.
N.A.
N.A.
N.A.
30.7
Protein Similarity:
100
N.A.
96.3
84
N.A.
85.7
86.4
N.A.
84
83.2
N.A.
70.8
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
N.A.
93.3
20
N.A.
20
20
N.A.
80
80
N.A.
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
93.3
26.6
N.A.
26.6
33.3
N.A.
86.6
86.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
23
23
34
23
0
0
23
0
56
12
0
0
0
23
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
56
12
23
0
78
0
56
0
0
0
0
0
12
0
0
% D
% Glu:
0
0
0
0
0
12
0
0
0
23
0
56
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
12
12
0
0
34
12
67
0
% K
% Leu:
0
23
12
56
12
12
12
34
23
23
78
0
56
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
12
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
12
12
0
0
23
12
56
% R
% Ser:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
34
12
0
12
0
0
0
0
34
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
12
12
0
78
0
56
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _