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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC7
All Species:
15.45
Human Site:
S146
Identified Species:
37.78
UniProt:
Q8N3Z6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z6
NP_115602.2
543
63052
S146
K
P
K
S
E
E
R
S
G
V
I
R
E
V
M
Chimpanzee
Pan troglodytes
XP_001169534
543
63034
S146
K
P
K
S
E
E
R
S
G
V
I
R
E
V
M
Rhesus Macaque
Macaca mulatta
XP_001114863
543
63168
S146
K
P
K
H
E
E
R
S
D
V
I
R
E
V
M
Dog
Lupus familis
XP_538733
544
63251
P145
Q
P
K
P
E
E
M
P
G
T
I
R
E
V
M
Cat
Felis silvestris
Mouse
Mus musculus
B1AX39
541
62982
P143
K
P
K
P
E
E
R
P
G
V
I
R
E
V
M
Rat
Rattus norvegicus
B1WC15
542
63308
P143
K
P
E
P
E
E
S
P
S
T
I
R
E
V
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509565
566
65060
S158
K
S
E
T
G
K
R
S
R
V
I
Q
E
V
L
Chicken
Gallus gallus
XP_424418
619
69362
P217
L
T
S
V
S
S
G
P
L
T
V
Q
E
V
M
Frog
Xenopus laevis
A1L2T6
563
64391
S162
N
S
S
S
K
N
Y
S
G
G
Y
V
Q
E
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199064
921
104738
S215
A
T
E
P
S
A
T
S
S
R
T
S
K
V
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.3
73.5
N.A.
64.8
64.8
N.A.
54.5
36.5
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
22.1
Protein Similarity:
100
99.6
97.6
82.1
N.A.
77.1
76.9
N.A.
69.7
52
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
34.6
P-Site Identity:
100
100
86.6
66.6
N.A.
86.6
60
N.A.
46.6
20
20
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
73.3
N.A.
86.6
66.6
N.A.
80
33.3
40
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
0
0
30
0
60
60
0
0
0
0
0
0
80
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
50
10
0
0
0
0
0
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
70
0
0
0
0
% I
% Lys:
60
0
50
0
10
10
0
0
0
0
0
0
10
0
0
% K
% Leu:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
70
% M
% Asn:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
60
0
40
0
0
0
40
0
0
0
0
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
20
10
0
0
% Q
% Arg:
0
0
0
0
0
0
50
0
10
10
0
60
0
0
0
% R
% Ser:
0
20
20
30
20
10
10
60
20
0
0
10
0
0
0
% S
% Thr:
0
20
0
10
0
0
10
0
0
30
10
0
0
0
0
% T
% Val:
0
0
0
10
0
0
0
0
0
50
10
10
0
90
20
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _