KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
C4orf37
All Species:
4.55
Human Site:
S423
Identified Species:
11.11
UniProt:
Q8N412
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N412
NP_777612.1
459
50660
S423
I
P
L
F
V
K
A
S
K
R
F
E
E
S
K
Chimpanzee
Pan troglodytes
XP_001165076
459
50675
S423
I
P
L
F
V
K
A
S
K
R
F
E
E
S
K
Rhesus Macaque
Macaca mulatta
XP_001098368
419
46365
K393
A
T
P
R
C
L
E
K
I
T
D
G
P
A
A
Dog
Lupus familis
XP_544989
731
80083
P633
Y
R
S
L
F
P
D
P
W
W
T
F
D
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8C8J0
561
62680
P494
I
I
S
F
V
K
G
P
K
R
F
Q
E
F
H
Rat
Rattus norvegicus
A1A5R9
563
63406
P496
I
I
S
F
V
K
A
P
R
R
F
E
E
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511793
545
60914
N492
I
L
R
V
R
L
A
N
G
T
L
E
R
F
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Q3KQ80
352
38888
P326
D
V
S
G
K
S
L
P
G
P
G
A
Y
H
P
Zebra Danio
Brachydanio rerio
Q08BC4
562
61729
R503
L
I
I
S
K
E
D
R
F
K
D
P
K
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782571
586
63663
L519
D
T
V
K
L
S
L
L
V
G
K
D
Q
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
51.8
46.6
N.A.
49.5
50.9
N.A.
20
N.A.
20.4
30.9
N.A.
N.A.
N.A.
N.A.
31.5
Protein Similarity:
100
99.3
59
51.5
N.A.
62
63.4
N.A.
35.7
N.A.
34.6
47.8
N.A.
N.A.
N.A.
N.A.
46.4
P-Site Identity:
100
100
0
0
N.A.
53.3
60
N.A.
20
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
6.6
6.6
N.A.
60
73.3
N.A.
26.6
N.A.
0
40
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
40
0
0
0
0
10
0
10
20
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
20
0
0
0
0
0
20
0
0
0
20
10
10
10
0
% D
% Glu:
0
0
0
0
0
10
10
0
0
0
0
40
40
0
10
% E
% Phe:
0
0
0
40
10
0
0
0
10
0
40
10
0
30
10
% F
% Gly:
0
0
0
10
0
0
10
0
20
10
10
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% H
% Ile:
50
30
10
0
0
0
0
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
10
20
40
0
10
30
10
10
0
10
0
20
% K
% Leu:
10
10
20
10
10
20
20
10
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
20
10
0
0
10
0
40
0
10
0
10
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
10
% Q
% Arg:
0
10
10
10
10
0
0
10
10
40
0
0
10
10
0
% R
% Ser:
0
0
40
10
0
20
0
20
0
0
0
0
0
20
0
% S
% Thr:
0
20
0
0
0
0
0
0
0
20
10
0
0
0
0
% T
% Val:
0
10
10
10
40
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _