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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A45
All Species:
24.24
Human Site:
T34
Identified Species:
44.44
UniProt:
Q8N413
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N413
NP_001070709.1
288
31906
T34
K
V
R
L
Q
T
Q
T
T
Y
R
G
I
V
D
Chimpanzee
Pan troglodytes
XP_508552
288
31811
T34
K
V
R
L
Q
T
Q
T
T
Y
R
G
I
V
D
Rhesus Macaque
Macaca mulatta
XP_001113849
288
31847
T34
K
V
R
L
Q
T
Q
T
T
Y
R
G
I
V
D
Dog
Lupus familis
XP_540861
353
38674
T34
K
V
R
L
Q
T
Q
T
T
Y
Q
G
I
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFJ7
288
31671
S34
K
V
R
L
Q
T
Q
S
T
Y
Q
G
I
V
D
Rat
Rattus norvegicus
Q6J329
310
33599
A31
K
V
K
I
Q
T
E
A
K
Y
T
S
I
W
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518172
268
28808
P19
G
E
G
D
T
P
G
P
A
P
P
P
P
E
G
Chicken
Gallus gallus
XP_414625
324
34605
Q55
E
T
R
L
Q
A
G
Q
G
Y
G
N
T
L
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A4QNX2
288
31518
T34
K
V
R
L
Q
T
Q
T
G
Y
S
G
F
W
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQG4
306
32934
P47
K
V
R
L
Q
T
M
P
R
P
A
P
G
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27257
312
33116
P36
K
V
R
I
Q
T
M
P
M
P
K
P
G
E
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93XM7
300
31004
P36
K
V
K
L
Q
S
Q
P
T
P
A
P
G
Q
L
Baker's Yeast
Sacchar. cerevisiae
P38087
329
36537
T66
K
V
R
L
Q
T
A
T
T
R
T
T
T
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.5
71.3
N.A.
85
41.2
N.A.
44.7
40.1
N.A.
46.8
N.A.
34.6
N.A.
29.8
N.A.
Protein Similarity:
100
99.6
98.6
76.7
N.A.
92.7
60.6
N.A.
56.2
57.4
N.A.
63.5
N.A.
49.6
N.A.
46.7
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
86.6
40
N.A.
0
26.6
N.A.
66.6
N.A.
40
N.A.
33.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
0
46.6
N.A.
66.6
N.A.
40
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.3
26.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.6
44.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
8
8
8
0
16
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
39
% D
% Glu:
8
8
0
0
0
0
8
0
0
0
0
0
0
24
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
8
0
0
0
16
0
16
0
8
47
24
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
16
0
0
0
0
0
0
0
0
47
8
0
% I
% Lys:
85
0
16
0
0
0
0
0
8
0
8
0
0
0
8
% K
% Leu:
0
0
0
77
0
0
0
0
0
0
0
0
0
16
8
% L
% Met:
0
0
0
0
0
0
16
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% N
% Pro:
0
0
0
0
0
8
0
31
0
31
8
31
8
0
0
% P
% Gln:
0
0
0
0
93
0
54
8
0
0
16
0
0
8
16
% Q
% Arg:
0
0
77
0
0
0
0
0
8
8
24
0
0
0
0
% R
% Ser:
0
0
0
0
0
8
0
8
0
0
8
8
0
0
0
% S
% Thr:
0
8
0
0
8
77
0
47
54
0
16
8
16
0
0
% T
% Val:
0
85
0
0
0
0
0
0
0
0
0
0
0
31
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
62
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _