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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A45 All Species: 28.18
Human Site: Y239 Identified Species: 51.67
UniProt: Q8N413 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N413 NP_001070709.1 288 31906 Y239 D G L R R R V Y Q G M L D C M
Chimpanzee Pan troglodytes XP_508552 288 31811 Y239 D G L R R R V Y Q G M L D C M
Rhesus Macaque Macaca mulatta XP_001113849 288 31847 Y239 D G L R R R V Y Q G V L D C M
Dog Lupus familis XP_540861 353 38674 Y239 G G L K H R V Y R G V L D C M
Cat Felis silvestris
Mouse Mus musculus Q8CFJ7 288 31671 Y239 D G L K G R K Y G G M L D C M
Rat Rattus norvegicus Q6J329 310 33599 Y257 D G Q G Q Q R Y R G L L H C V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518172 268 28808 P220 P R G P A F D P A T L A H S L
Chicken Gallus gallus XP_414625 324 34605 Y267 D G V Y L N K Y K G I L D C I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A4QNX2 288 31518 Y239 D G V S G R R Y R G F L H C I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VQG4 306 32934 H252 A P E G T Y K H G I R S V F K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q27257 312 33116 D243 A P E G K Y P D G I R G V L R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q93XM7 300 31004 Y251 D D Y K N P R Y T G S M D A F
Baker's Yeast Sacchar. cerevisiae P38087 329 36537 K278 D L R K P K Y K N S I S Y V A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.5 71.3 N.A. 85 41.2 N.A. 44.7 40.1 N.A. 46.8 N.A. 34.6 N.A. 29.8 N.A.
Protein Similarity: 100 99.6 98.6 76.7 N.A. 92.7 60.6 N.A. 56.2 57.4 N.A. 63.5 N.A. 49.6 N.A. 46.7 N.A.
P-Site Identity: 100 100 93.3 66.6 N.A. 73.3 40 N.A. 0 46.6 N.A. 46.6 N.A. 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 80 73.3 N.A. 13.3 73.3 N.A. 66.6 N.A. 6.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 33.3 26.7 N.A.
Protein Similarity: N.A. N.A. N.A. 48.6 44.9 N.A.
P-Site Identity: N.A. N.A. N.A. 26.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 16 0 0 0 8 0 0 0 8 0 0 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 62 0 % C
% Asp: 70 8 0 0 0 0 8 8 0 0 0 0 54 0 0 % D
% Glu: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 8 0 0 8 8 % F
% Gly: 8 62 8 24 16 0 0 0 24 70 0 8 0 0 0 % G
% His: 0 0 0 0 8 0 0 8 0 0 0 0 24 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 16 16 0 0 0 16 % I
% Lys: 0 0 0 31 8 8 24 8 8 0 0 0 0 0 8 % K
% Leu: 0 8 39 0 8 0 0 0 0 0 16 62 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 24 8 0 0 39 % M
% Asn: 0 0 0 0 8 8 0 0 8 0 0 0 0 0 0 % N
% Pro: 8 16 0 8 8 8 8 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 8 8 0 0 24 0 0 0 0 0 0 % Q
% Arg: 0 8 8 24 24 47 24 0 24 0 16 0 0 0 8 % R
% Ser: 0 0 0 8 0 0 0 0 0 8 8 16 0 8 0 % S
% Thr: 0 0 0 0 8 0 0 0 8 8 0 0 0 0 0 % T
% Val: 0 0 16 0 0 0 31 0 0 0 16 0 16 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 8 0 16 8 70 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _