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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC3
All Species:
4.24
Human Site:
S237
Identified Species:
9.33
UniProt:
Q8N427
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N427
NP_057700.3
588
67270
S237
G
S
K
H
N
P
P
S
E
E
T
E
P
Q
T
Chimpanzee
Pan troglodytes
XP_527723
588
67233
S237
G
S
K
H
N
P
P
S
E
E
T
E
P
Q
P
Rhesus Macaque
Macaca mulatta
XP_001101594
588
67091
P237
G
S
K
H
N
T
P
P
E
E
T
E
P
Q
P
Dog
Lupus familis
XP_851794
589
68040
L237
G
D
E
E
Q
P
D
L
K
E
T
E
P
D
P
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
E237
E
D
S
E
V
I
Q
E
E
T
L
P
Q
T
D
Rat
Rattus norvegicus
Q715S9
587
67293
E237
G
E
D
T
E
V
I
E
E
E
A
L
P
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
V31
L
C
S
K
G
L
T
V
V
D
V
Y
Q
R
W
Chicken
Gallus gallus
XP_426021
577
65924
P239
K
K
A
T
D
A
I
P
L
W
T
E
L
H
E
Frog
Xenopus laevis
NP_001085047
625
70225
I242
S
E
E
D
E
D
V
I
P
A
W
R
E
F
I
Zebra Danio
Brachydanio rerio
NP_001082944
531
60418
A212
D
F
Y
Q
H
K
A
A
E
P
Y
F
Q
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786989
816
89219
V285
G
N
T
G
E
G
V
V
S
D
I
R
N
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
90.8
68.5
N.A.
63.4
61.2
N.A.
25.1
47.9
39.6
35
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
98.8
95.2
82.8
N.A.
78.2
77.2
N.A.
40.1
70
59.6
54.9
N.A.
N.A.
N.A.
N.A.
43.2
P-Site Identity:
100
93.3
80
40
N.A.
6.6
33.3
N.A.
0
13.3
0
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
80
53.3
N.A.
6.6
40
N.A.
13.3
20
6.6
26.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
10
10
0
10
10
0
0
0
0
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
10
10
10
10
10
0
0
19
0
0
0
10
10
% D
% Glu:
10
19
19
19
28
0
0
19
55
46
0
46
10
10
10
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
55
0
0
10
10
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
28
10
0
0
0
0
0
0
0
0
10
0
% H
% Ile:
0
0
0
0
0
10
19
10
0
0
10
0
0
0
10
% I
% Lys:
10
10
28
10
0
10
0
0
10
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
10
0
10
10
0
10
10
10
10
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
28
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
28
28
19
10
10
0
10
46
0
28
% P
% Gln:
0
0
0
10
10
0
10
0
0
0
0
0
28
37
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
19
0
10
0
% R
% Ser:
10
28
19
0
0
0
0
19
10
0
0
0
0
0
10
% S
% Thr:
0
0
10
19
0
10
10
0
0
10
46
0
0
10
10
% T
% Val:
0
0
0
0
10
10
19
19
10
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _