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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC3
All Species:
8.79
Human Site:
S463
Identified Species:
19.33
UniProt:
Q8N427
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N427
NP_057700.3
588
67270
S463
L
I
K
P
H
A
T
S
E
Q
R
E
Q
I
L
Chimpanzee
Pan troglodytes
XP_527723
588
67233
S463
L
I
K
P
H
A
T
S
E
Q
R
E
Q
I
L
Rhesus Macaque
Macaca mulatta
XP_001101594
588
67091
S463
L
I
K
P
H
A
T
S
E
Q
I
E
K
I
L
Dog
Lupus familis
XP_851794
589
68040
H459
L
I
K
P
H
V
T
H
E
Q
R
E
E
I
L
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
H460
L
I
K
P
H
V
T
H
K
E
R
M
E
I
L
Rat
Rattus norvegicus
Q715S9
587
67293
H461
L
I
K
P
H
V
S
H
K
E
R
M
E
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
E216
K
A
K
E
E
T
F
E
K
L
V
E
F
M
S
Chicken
Gallus gallus
XP_426021
577
65924
N453
I
K
P
D
A
A
K
N
H
K
D
E
I
M
Q
Frog
Xenopus laevis
NP_001085047
625
70225
E461
T
I
K
P
D
A
L
E
E
H
R
D
E
I
L
Zebra Danio
Brachydanio rerio
NP_001082944
531
60418
L399
V
E
H
W
R
N
I
L
G
P
K
D
P
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786989
816
89219
G503
V
I
K
P
D
A
A
G
E
H
K
E
A
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
90.8
68.5
N.A.
63.4
61.2
N.A.
25.1
47.9
39.6
35
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
98.8
95.2
82.8
N.A.
78.2
77.2
N.A.
40.1
70
59.6
54.9
N.A.
N.A.
N.A.
N.A.
43.2
P-Site Identity:
100
100
86.6
80
N.A.
60
53.3
N.A.
13.3
13.3
53.3
6.6
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
80
80
N.A.
26.6
40
66.6
26.6
N.A.
N.A.
N.A.
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
10
55
10
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
19
0
0
0
0
0
10
19
0
0
0
% D
% Glu:
0
10
0
10
10
0
0
19
55
19
0
64
37
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% G
% His:
0
0
10
0
55
0
0
28
10
19
0
0
0
0
0
% H
% Ile:
10
73
0
0
0
0
10
0
0
0
10
0
10
82
10
% I
% Lys:
10
10
82
0
0
0
10
0
28
10
19
0
10
0
10
% K
% Leu:
55
0
0
0
0
0
10
10
0
10
0
0
0
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
19
0
19
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
73
0
0
0
0
0
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
37
0
0
19
0
10
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
55
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
10
28
0
0
0
0
0
0
10
% S
% Thr:
10
0
0
0
0
10
46
0
0
0
0
0
0
0
0
% T
% Val:
19
0
0
0
0
28
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _