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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC3
All Species:
22.42
Human Site:
S548
Identified Species:
49.33
UniProt:
Q8N427
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N427
NP_057700.3
588
67270
S548
P
E
E
A
K
L
L
S
P
D
S
I
R
A
Q
Chimpanzee
Pan troglodytes
XP_527723
588
67233
S548
P
E
E
A
K
V
L
S
P
D
S
I
R
A
Q
Rhesus Macaque
Macaca mulatta
XP_001101594
588
67091
S548
P
E
E
A
K
V
L
S
P
D
S
I
R
S
R
Dog
Lupus familis
XP_851794
589
68040
S544
P
D
E
A
K
L
L
S
P
D
S
I
R
A
H
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
S545
P
E
E
A
K
L
L
S
P
E
S
L
R
A
K
Rat
Rattus norvegicus
Q715S9
587
67293
S546
P
E
E
A
K
L
L
S
P
N
S
L
R
A
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
F298
L
A
Y
F
F
P
G
F
K
V
S
D
E
T
A
Chicken
Gallus gallus
XP_426021
577
65924
C537
P
E
V
A
K
E
S
C
P
E
S
I
R
A
Q
Frog
Xenopus laevis
NP_001085047
625
70225
L546
P
A
E
A
Q
K
V
L
P
D
S
L
R
G
K
Zebra Danio
Brachydanio rerio
NP_001082944
531
60418
D481
F
T
I
S
Q
L
K
D
T
I
L
S
R
E
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786989
816
89219
A588
P
D
Y
A
R
E
H
A
P
E
S
L
R
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
90.8
68.5
N.A.
63.4
61.2
N.A.
25.1
47.9
39.6
35
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
98.8
95.2
82.8
N.A.
78.2
77.2
N.A.
40.1
70
59.6
54.9
N.A.
N.A.
N.A.
N.A.
43.2
P-Site Identity:
100
93.3
80
86.6
N.A.
80
80
N.A.
6.6
66.6
46.6
13.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
6.6
73.3
73.3
26.6
N.A.
N.A.
N.A.
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
82
0
0
0
10
0
0
0
0
0
64
10
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
19
0
0
0
0
0
10
0
46
0
10
0
0
0
% D
% Glu:
0
55
64
0
0
19
0
0
0
28
0
0
10
10
0
% E
% Phe:
10
0
0
10
10
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
10
0
0
0
0
0
0
10
0
46
0
0
0
% I
% Lys:
0
0
0
0
64
10
10
0
10
0
0
0
0
0
19
% K
% Leu:
10
0
0
0
0
46
55
10
0
0
10
37
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% N
% Pro:
82
0
0
0
0
10
0
0
82
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
28
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
91
0
19
% R
% Ser:
0
0
0
10
0
0
10
55
0
0
91
10
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
0
0
0
0
10
0
% T
% Val:
0
0
10
0
0
19
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
19
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _