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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNDC3
All Species:
3.94
Human Site:
T246
Identified Species:
8.67
UniProt:
Q8N427
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N427
NP_057700.3
588
67270
T246
E
T
E
P
Q
T
D
T
E
P
N
E
R
S
E
Chimpanzee
Pan troglodytes
XP_527723
588
67233
T246
E
T
E
P
Q
P
D
T
E
P
N
E
P
S
E
Rhesus Macaque
Macaca mulatta
XP_001101594
588
67091
R246
E
T
E
P
Q
P
D
R
A
P
N
K
P
S
E
Dog
Lupus familis
XP_851794
589
68040
M246
E
T
E
P
D
P
E
M
E
A
K
E
A
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q715T0
586
66839
E246
T
L
P
Q
T
D
T
E
E
E
P
G
V
L
E
Rat
Rattus norvegicus
Q715S9
587
67293
D246
E
A
L
P
Q
S
D
D
E
E
E
P
D
P
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510205
329
37121
G40
D
V
Y
Q
R
W
C
G
P
C
K
T
V
V
S
Chicken
Gallus gallus
XP_426021
577
65924
N248
W
T
E
L
H
E
T
N
E
S
M
P
D
E
T
Frog
Xenopus laevis
NP_001085047
625
70225
P251
A
W
R
E
F
I
G
P
T
D
V
E
I
A
K
Zebra Danio
Brachydanio rerio
NP_001082944
531
60418
Q221
P
Y
F
Q
E
L
V
Q
F
M
S
S
G
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786989
816
89219
P294
D
I
R
N
L
L
G
P
K
D
I
E
V
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
90.8
68.5
N.A.
63.4
61.2
N.A.
25.1
47.9
39.6
35
N.A.
N.A.
N.A.
N.A.
27
Protein Similarity:
100
98.8
95.2
82.8
N.A.
78.2
77.2
N.A.
40.1
70
59.6
54.9
N.A.
N.A.
N.A.
N.A.
43.2
P-Site Identity:
100
86.6
66.6
46.6
N.A.
13.3
33.3
N.A.
0
20
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
86.6
73.3
53.3
N.A.
13.3
40
N.A.
13.3
20
20
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
0
0
0
0
10
10
0
0
10
19
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% C
% Asp:
19
0
0
0
10
10
37
10
0
19
0
0
19
10
0
% D
% Glu:
46
0
46
10
10
10
10
10
55
19
10
46
0
10
46
% E
% Phe:
0
0
10
0
10
0
0
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
19
10
0
0
0
10
10
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
10
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
19
10
0
0
19
% K
% Leu:
0
10
10
10
10
19
0
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
28
0
0
0
0
% N
% Pro:
10
0
10
46
0
28
0
19
10
28
10
19
19
19
0
% P
% Gln:
0
0
0
28
37
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
19
0
10
0
0
10
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
0
0
10
0
0
0
10
10
10
0
28
19
% S
% Thr:
10
46
0
0
10
10
19
19
10
0
0
10
0
0
10
% T
% Val:
0
10
0
0
0
0
10
0
0
0
10
0
28
10
0
% V
% Trp:
10
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _