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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RASGEF1C
All Species:
20
Human Site:
S17
Identified Species:
40
UniProt:
Q8N431
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N431
NP_778232.2
466
52870
S17
M
V
T
P
G
S
L
S
P
P
P
T
E
P
T
Chimpanzee
Pan troglodytes
XP_518156
546
61226
S97
M
V
T
P
G
S
L
S
P
P
P
T
E
P
T
Rhesus Macaque
Macaca mulatta
XP_001102791
466
52809
S17
M
V
T
P
G
S
L
S
P
P
T
T
E
P
T
Dog
Lupus familis
XP_538583
684
76123
G82
M
V
T
P
G
S
L
G
P
P
P
T
E
P
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9D300
466
52705
S17
M
V
T
P
G
S
L
S
P
P
P
T
E
S
T
Rat
Rattus norvegicus
NP_001101743
466
52800
S17
M
V
T
P
G
S
L
S
P
P
P
I
D
S
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507622
522
60072
G65
M
L
G
S
S
C
S
G
Q
V
Q
P
D
M
G
Chicken
Gallus gallus
XP_414615
480
55173
S26
M
F
T
P
C
S
F
S
P
H
L
H
S
S
K
Frog
Xenopus laevis
NP_001086251
419
48694
I22
I
F
I
H
P
Y
E
I
L
A
K
V
G
Q
M
Zebra Danio
Brachydanio rerio
Q6DHR3
514
59871
N59
Y
G
S
T
N
G
Y
N
K
N
L
Y
K
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396254
713
79278
Q268
N
G
S
G
T
D
H
Q
D
I
R
D
G
A
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_789261
598
68657
S149
G
L
H
A
R
E
K
S
P
E
I
K
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.1
98
63
N.A.
94.6
94.8
N.A.
51.3
81
50.4
62.8
N.A.
N.A.
37.3
N.A.
44.4
Protein Similarity:
100
85.1
98.9
66.2
N.A.
97.4
97.4
N.A.
66
87.9
65.4
73.9
N.A.
N.A.
48.3
N.A.
56.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
80
N.A.
6.6
40
0
0
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
86.6
N.A.
20
40
6.6
20
N.A.
N.A.
6.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
9
0
0
0
17
9
% A
% Cys:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
0
0
9
0
0
9
17
0
0
% D
% Glu:
0
0
0
0
0
9
9
0
0
9
0
0
42
9
9
% E
% Phe:
0
17
0
0
0
0
9
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
9
50
9
0
17
0
0
0
0
17
0
9
% G
% His:
0
0
9
9
0
0
9
0
0
9
0
9
0
0
0
% H
% Ile:
9
0
9
0
0
0
0
9
0
9
9
9
0
0
0
% I
% Lys:
0
0
0
0
0
0
9
0
9
0
9
9
17
0
17
% K
% Leu:
0
17
0
0
0
0
50
0
9
0
17
0
0
0
0
% L
% Met:
67
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% M
% Asn:
9
0
0
0
9
0
0
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
59
9
0
0
0
67
50
42
9
0
34
0
% P
% Gln:
0
0
0
0
0
0
0
9
9
0
9
0
0
9
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% R
% Ser:
0
0
17
9
9
59
9
59
0
0
0
0
9
25
0
% S
% Thr:
0
0
59
9
9
0
0
0
0
0
9
42
0
0
50
% T
% Val:
0
50
0
0
0
0
0
0
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
9
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _