Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUF1 All Species: 7.88
Human Site: S50 Identified Species: 14.44
UniProt: Q8N442 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N442 NP_068746.2 669 74328 S50 W A T D R L Y S S A E F K E K
Chimpanzee Pan troglodytes XP_517175 669 74318 S50 W A T N R L Y S S A E F K E K
Rhesus Macaque Macaca mulatta XP_001099650 663 73937 F48 R V Y S S A E F K E K L D M S
Dog Lupus familis XP_539246 890 98288 P271 E Q F V T L G P G V V V G E K
Cat Felis silvestris
Mouse Mus musculus Q8C3X4 651 72444 S54 V E D I R N F S I I A H V D H
Rat Rattus norvegicus NP_001100685 659 73188 P48 A A E L K E K P D M S R F P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515927 641 71161 G52 I I A H V D H G K S T L A D R
Chicken Gallus gallus XP_001232470 660 74204 K48 Y S S R D K E K I D M S A Y P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664348 672 75290 S56 G S V R D L S S S A T E K E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396034 626 70950 L51 S T L A D R L L E I T G A I K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791097 640 71703 G53 I I A H V D H G K S T L A D R
Poplar Tree Populus trichocarpa XP_002323840 611 67671 D48 H G Q P Q Y L D K L Q V E R E
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198806 663 73577 R48 Y G F S S D S R Q S S K E P T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96.8 70.1 N.A. 87.5 87.5 N.A. 80.1 77.7 N.A. 74.1 N.A. N.A. 54.1 N.A. 64.1
Protein Similarity: 100 99.8 97.9 72.5 N.A. 93.4 94 N.A. 87.8 87.5 N.A. 85.5 N.A. N.A. 69.6 N.A. 79.3
P-Site Identity: 100 93.3 0 20 N.A. 13.3 6.6 N.A. 0 0 N.A. 40 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 6.6 20 N.A. 26.6 13.3 N.A. 26.6 20 N.A. 46.6 N.A. N.A. 6.6 N.A. 26.6
Percent
Protein Identity: 47.6 N.A. N.A. 55.7 N.A. N.A.
Protein Similarity: 66.2 N.A. N.A. 72.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 24 16 8 0 8 0 0 0 24 8 0 31 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 8 24 24 0 8 8 8 0 0 8 24 0 % D
% Glu: 8 8 8 0 0 8 16 0 8 8 16 8 16 31 8 % E
% Phe: 0 0 16 0 0 0 8 8 0 0 0 16 8 0 0 % F
% Gly: 8 16 0 0 0 0 8 16 8 0 0 8 8 0 0 % G
% His: 8 0 0 16 0 0 16 0 0 0 0 8 0 0 8 % H
% Ile: 16 16 0 8 0 0 0 0 16 16 0 0 0 8 0 % I
% Lys: 0 0 0 0 8 8 8 8 31 0 8 8 24 0 31 % K
% Leu: 0 0 8 8 0 31 16 8 0 8 0 24 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % M
% Asn: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 16 0 0 0 0 0 16 8 % P
% Gln: 0 8 8 0 8 0 0 0 8 0 8 0 0 0 0 % Q
% Arg: 8 0 0 16 24 8 0 8 0 0 0 8 0 8 16 % R
% Ser: 8 16 8 16 16 0 16 31 24 24 16 8 0 0 8 % S
% Thr: 0 8 16 0 8 0 0 0 0 0 31 0 0 0 16 % T
% Val: 8 8 8 8 16 0 0 0 0 8 8 16 8 0 8 % V
% Trp: 16 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 16 0 8 0 0 8 16 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _