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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GUF1 All Species: 6.36
Human Site: T45 Identified Species: 11.67
UniProt: Q8N442 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N442 NP_068746.2 669 74328 T45 A A P E S W A T D R L Y S S A
Chimpanzee Pan troglodytes XP_517175 669 74318 T45 A A P E S W A T N R L Y S S A
Rhesus Macaque Macaca mulatta XP_001099650 663 73937 Y43 S W P T C R V Y S S A E F K E
Dog Lupus familis XP_539246 890 98288 F266 A G E G G E Q F V T L G P G V
Cat Felis silvestris
Mouse Mus musculus Q8C3X4 651 72444 D49 M S R F P V E D I R N F S I I
Rat Rattus norvegicus NP_001100685 659 73188 E43 C R L F S A A E L K E K P D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515927 641 71161 A47 I R N F S I I A H V D H G K S
Chicken Gallus gallus XP_001232470 660 74204 S43 A C Q R F Y S S R D K E K I D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002664348 672 75290 V51 W M K S L G S V R D L S S S A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396034 626 70950 L46 V D H G K S T L A D R L L E I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791097 640 71703 A48 I R N F S I I A H V D H G K S
Poplar Tree Populus trichocarpa XP_002323840 611 67671 Q43 T I K R G H G Q P Q Y L D K L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_198806 663 73577 F43 G L Y Q A Y G F S S D S R Q S
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 96.8 70.1 N.A. 87.5 87.5 N.A. 80.1 77.7 N.A. 74.1 N.A. N.A. 54.1 N.A. 64.1
Protein Similarity: 100 99.8 97.9 72.5 N.A. 93.4 94 N.A. 87.8 87.5 N.A. 85.5 N.A. N.A. 69.6 N.A. 79.3
P-Site Identity: 100 93.3 6.6 13.3 N.A. 13.3 13.3 N.A. 6.6 6.6 N.A. 26.6 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 13.3 13.3 N.A. 26.6 20 N.A. 20 26.6 N.A. 33.3 N.A. N.A. 0 N.A. 20
Percent
Protein Identity: 47.6 N.A. N.A. 55.7 N.A. N.A.
Protein Similarity: 66.2 N.A. N.A. 72.6 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 31 16 0 0 8 8 24 16 8 0 8 0 0 0 24 % A
% Cys: 8 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 8 8 24 24 0 8 8 8 % D
% Glu: 0 0 8 16 0 8 8 8 0 0 8 16 0 8 8 % E
% Phe: 0 0 0 31 8 0 0 16 0 0 0 8 8 0 0 % F
% Gly: 8 8 0 16 16 8 16 0 0 0 0 8 16 8 0 % G
% His: 0 0 8 0 0 8 0 0 16 0 0 16 0 0 0 % H
% Ile: 16 8 0 0 0 16 16 0 8 0 0 0 0 16 16 % I
% Lys: 0 0 16 0 8 0 0 0 0 8 8 8 8 31 0 % K
% Leu: 0 8 8 0 8 0 0 8 8 0 31 16 8 0 8 % L
% Met: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 16 0 0 0 0 0 8 0 8 0 0 0 0 % N
% Pro: 0 0 24 0 8 0 0 0 8 0 0 0 16 0 0 % P
% Gln: 0 0 8 8 0 0 8 8 0 8 0 0 0 8 0 % Q
% Arg: 0 24 8 16 0 8 0 0 16 24 8 0 8 0 0 % R
% Ser: 8 8 0 8 39 8 16 8 16 16 0 16 31 24 24 % S
% Thr: 8 0 0 8 0 0 8 16 0 8 0 0 0 0 0 % T
% Val: 8 0 0 0 0 8 8 8 8 16 0 0 0 0 8 % V
% Trp: 8 8 0 0 0 16 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 16 0 8 0 0 8 16 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _