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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUF1
All Species:
11.82
Human Site:
T94
Identified Species:
21.67
UniProt:
Q8N442
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N442
NP_068746.2
669
74328
T94
R
L
L
E
L
T
G
T
I
D
K
T
K
N
N
Chimpanzee
Pan troglodytes
XP_517175
669
74318
T94
R
L
L
E
L
T
G
T
I
D
K
T
K
N
N
Rhesus Macaque
Macaca mulatta
XP_001099650
663
73937
T92
L
T
G
T
I
D
K
T
E
N
N
K
Q
V
L
Dog
Lupus familis
XP_539246
890
98288
A315
R
L
L
E
L
T
G
A
I
D
K
T
K
N
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3X4
651
72444
I98
Q
V
E
R
E
R
G
I
T
V
K
A
Q
T
A
Rat
Rattus norvegicus
NP_001100685
659
73188
K92
I
D
K
T
Q
K
N
K
Q
V
L
D
K
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515927
641
71161
S96
T
V
K
A
Q
T
A
S
L
F
Y
H
F
R
G
Chicken
Gallus gallus
XP_001232470
660
74204
N92
T
I
A
K
T
D
R
N
K
Q
V
L
D
K
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664348
672
75290
A100
R
L
L
E
M
T
G
A
I
A
K
T
A
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396034
626
70950
Y95
Y
T
Y
N
G
I
N
Y
L
L
N
L
I
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791097
640
71703
S97
T
V
K
A
Q
T
A
S
M
V
Y
H
Y
K
G
Poplar Tree
Populus trichocarpa
XP_002323840
611
67671
I92
P
T
Y
L
L
N
L
I
D
T
P
G
H
V
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198806
663
73577
T92
R
L
M
E
L
T
G
T
I
K
K
G
H
G
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
70.1
N.A.
87.5
87.5
N.A.
80.1
77.7
N.A.
74.1
N.A.
N.A.
54.1
N.A.
64.1
Protein Similarity:
100
99.8
97.9
72.5
N.A.
93.4
94
N.A.
87.8
87.5
N.A.
85.5
N.A.
N.A.
69.6
N.A.
79.3
P-Site Identity:
100
100
6.6
93.3
N.A.
13.3
6.6
N.A.
6.6
0
N.A.
66.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
26.6
93.3
N.A.
33.3
6.6
N.A.
26.6
13.3
N.A.
80
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
47.6
N.A.
N.A.
55.7
N.A.
N.A.
Protein Similarity:
66.2
N.A.
N.A.
72.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
60
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
16
0
0
16
16
0
8
0
8
8
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
16
0
0
8
24
0
8
8
8
8
% D
% Glu:
0
0
8
39
8
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% F
% Gly:
0
0
8
0
8
0
47
0
0
0
0
16
0
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
16
16
0
0
% H
% Ile:
8
8
0
0
8
8
0
16
39
0
0
0
8
0
0
% I
% Lys:
0
0
24
8
0
8
8
8
8
8
47
8
31
16
0
% K
% Leu:
8
39
31
8
39
0
8
0
16
8
8
16
0
8
16
% L
% Met:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
8
16
8
0
8
16
0
0
24
31
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
8
0
0
0
24
0
0
0
8
8
0
0
16
0
16
% Q
% Arg:
39
0
0
8
0
8
8
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
0
0
0
0
0
16
0
0
0
0
0
8
0
% S
% Thr:
24
24
0
16
8
54
0
31
8
8
0
31
0
8
8
% T
% Val:
0
24
0
0
0
0
0
0
0
24
8
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
0
0
0
0
8
0
0
16
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _