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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUF1
All Species:
40.3
Human Site:
Y469
Identified Species:
73.89
UniProt:
Q8N442
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N442
NP_068746.2
669
74328
Y469
D
K
S
K
V
T
E
Y
L
E
P
V
V
L
G
Chimpanzee
Pan troglodytes
XP_517175
669
74318
Y469
D
K
S
K
V
T
E
Y
L
E
P
V
V
L
G
Rhesus Macaque
Macaca mulatta
XP_001099650
663
73937
Y463
D
K
S
K
V
T
E
Y
L
E
P
V
V
L
G
Dog
Lupus familis
XP_539246
890
98288
Y690
D
K
S
K
V
T
E
Y
L
E
P
V
V
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8C3X4
651
72444
Y451
E
K
S
Q
V
T
E
Y
L
E
P
V
V
L
G
Rat
Rattus norvegicus
NP_001100685
659
73188
Y459
D
K
S
K
V
T
E
Y
L
E
P
V
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515927
641
71161
Y441
D
R
S
K
V
A
E
Y
L
E
P
T
V
L
G
Chicken
Gallus gallus
XP_001232470
660
74204
Y460
D
K
H
S
V
S
E
Y
L
E
P
T
V
L
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664348
672
75290
Y475
D
K
S
K
V
L
E
Y
L
E
P
M
V
T
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396034
626
70950
F430
D
P
Q
I
V
E
E
F
Y
E
P
M
V
L
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791097
640
71703
Y444
D
A
Q
R
V
V
E
Y
L
E
P
M
I
I
G
Poplar Tree
Populus trichocarpa
XP_002323840
611
67671
I422
A
S
W
E
P
T
V
I
A
T
I
I
I
P
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_198806
663
73577
S466
P
K
Y
R
V
T
A
S
W
E
P
T
V
I
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
70.1
N.A.
87.5
87.5
N.A.
80.1
77.7
N.A.
74.1
N.A.
N.A.
54.1
N.A.
64.1
Protein Similarity:
100
99.8
97.9
72.5
N.A.
93.4
94
N.A.
87.8
87.5
N.A.
85.5
N.A.
N.A.
69.6
N.A.
79.3
P-Site Identity:
100
100
100
100
N.A.
86.6
100
N.A.
80
73.3
N.A.
80
N.A.
N.A.
53.3
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
80
N.A.
86.6
N.A.
N.A.
66.6
N.A.
80
Percent
Protein Identity:
47.6
N.A.
N.A.
55.7
N.A.
N.A.
Protein Similarity:
66.2
N.A.
N.A.
72.6
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
0
8
8
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
77
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
8
0
8
85
0
0
93
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
8
8
16
16
0
% I
% Lys:
0
70
0
54
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
77
0
0
0
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
24
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
0
0
8
0
0
0
0
0
93
0
0
8
0
% P
% Gln:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
16
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
62
8
0
8
0
8
0
0
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
62
0
0
0
8
0
24
0
8
0
% T
% Val:
0
0
0
0
93
8
8
0
0
0
0
47
85
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
77
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _