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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL16
All Species:
27.27
Human Site:
S250
Identified Species:
60
UniProt:
Q8N461
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N461
NP_699181.1
479
51658
S250
R
I
T
S
L
S
V
S
D
C
I
N
V
A
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118521
483
51972
S250
R
I
T
S
L
S
V
S
D
C
I
N
V
A
D
Dog
Lupus familis
XP_547211
483
52133
S254
R
I
T
S
L
S
V
S
D
C
I
N
V
A
D
Cat
Felis silvestris
Mouse
Mus musculus
A2RT62
479
51860
S250
R
I
T
S
L
S
V
S
D
C
I
N
V
A
D
Rat
Rattus norvegicus
Q5MJ12
479
51833
S250
R
I
T
S
L
S
V
S
D
C
I
N
V
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513564
217
22842
Chicken
Gallus gallus
XP_414720
437
47503
L214
E
F
I
D
N
Y
P
L
S
K
K
G
V
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334619
484
53683
S255
R
L
T
S
L
S
V
S
D
C
I
N
V
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729732
666
71670
A437
R
I
V
S
L
S
L
A
D
C
I
N
I
A
D
Honey Bee
Apis mellifera
XP_392431
413
45033
R197
R
L
Y
A
S
L
V
R
R
G
F
H
S
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780460
481
52568
S252
R
L
T
A
L
S
I
S
D
C
I
N
V
A
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90
96.6
N.A.
96.4
96.6
N.A.
34.4
75.3
N.A.
78.9
N.A.
42
40.5
N.A.
55
Protein Similarity:
100
N.A.
90.6
97.3
N.A.
97.4
97.4
N.A.
37.5
79.7
N.A.
86.5
N.A.
55.2
51.9
N.A.
69.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
6.6
N.A.
93.3
N.A.
73.3
13.3
N.A.
80
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
6.6
N.A.
100
N.A.
93.3
33.3
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
10
0
0
0
0
0
73
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
73
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
73
0
0
0
0
0
73
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
55
10
0
0
0
10
0
0
0
73
0
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
0
0
10
0
% K
% Leu:
0
28
0
0
73
10
10
10
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
73
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
82
0
0
0
0
0
0
10
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
64
10
73
0
64
10
0
0
0
10
0
10
% S
% Thr:
0
0
64
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
64
0
0
0
0
0
73
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _