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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL16
All Species:
21.82
Human Site:
S469
Identified Species:
48
UniProt:
Q8N461
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N461
NP_699181.1
479
51658
S469
P
E
L
F
K
Y
F
S
Q
H
L
P
R
C
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118521
483
51972
R469
T
A
K
A
M
A
R
R
R
E
P
K
P
H
P
Dog
Lupus familis
XP_547211
483
52133
S473
P
E
L
F
K
Y
F
S
Q
H
L
P
R
C
L
Cat
Felis silvestris
Mouse
Mus musculus
A2RT62
479
51860
S469
P
E
L
F
K
Y
F
S
Q
H
L
P
R
C
L
Rat
Rattus norvegicus
Q5MJ12
479
51833
S469
P
E
L
F
K
Y
F
S
Q
H
L
P
R
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513564
217
22842
T210
S
M
S
L
K
R
S
T
I
T
D
A
G
L
E
Chicken
Gallus gallus
XP_414720
437
47503
L423
Y
L
S
T
M
S
S
L
R
S
L
Y
L
R
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334619
484
53683
S474
A
E
L
F
K
Y
Y
S
Q
H
L
P
R
C
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729732
666
71670
K656
H
E
L
F
D
Y
L
K
E
H
L
P
R
C
L
Honey Bee
Apis mellifera
XP_392431
413
45033
L406
I
A
C
D
L
N
H
L
E
E
L
T
L
D
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780460
481
52568
S471
P
K
L
L
Q
Y
F
S
A
N
L
S
A
C
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90
96.6
N.A.
96.4
96.6
N.A.
34.4
75.3
N.A.
78.9
N.A.
42
40.5
N.A.
55
Protein Similarity:
100
N.A.
90.6
97.3
N.A.
97.4
97.4
N.A.
37.5
79.7
N.A.
86.5
N.A.
55.2
51.9
N.A.
69.8
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
80
N.A.
66.6
6.6
N.A.
46.6
P-Site Similarity:
100
N.A.
6.6
100
N.A.
100
100
N.A.
13.3
13.3
N.A.
93.3
N.A.
73.3
13.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
0
10
0
10
0
0
10
0
0
10
10
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
64
0
% C
% Asp:
0
0
0
10
10
0
0
0
0
0
10
0
0
10
0
% D
% Glu:
0
55
0
0
0
0
0
0
19
19
0
0
0
0
10
% E
% Phe:
0
0
0
55
0
0
46
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
10
0
0
55
0
0
0
10
0
% H
% Ile:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% I
% Lys:
0
10
10
0
55
0
0
10
0
0
0
10
0
0
0
% K
% Leu:
0
10
64
19
10
0
10
19
0
0
82
0
19
10
46
% L
% Met:
0
10
0
0
19
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
10
0
0
0
0
0
% N
% Pro:
46
0
0
0
0
0
0
0
0
0
10
55
10
0
10
% P
% Gln:
0
0
0
0
10
0
0
0
46
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
10
10
19
0
0
0
55
10
10
% R
% Ser:
10
0
19
0
0
10
19
55
0
10
0
10
0
0
0
% S
% Thr:
10
0
0
10
0
0
0
10
0
10
0
10
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% W
% Tyr:
10
0
0
0
0
64
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _