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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL16
All Species:
27.27
Human Site:
T461
Identified Species:
60
UniProt:
Q8N461
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N461
NP_699181.1
479
51658
T461
L
T
N
C
P
G
A
T
P
E
L
F
K
Y
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118521
483
51972
A461
E
G
C
Q
G
K
Q
A
T
A
K
A
M
A
R
Dog
Lupus familis
XP_547211
483
52133
T465
L
T
N
C
P
G
A
T
P
E
L
F
K
Y
F
Cat
Felis silvestris
Mouse
Mus musculus
A2RT62
479
51860
T461
L
T
N
C
P
G
A
T
P
E
L
F
K
Y
F
Rat
Rattus norvegicus
Q5MJ12
479
51833
T461
L
T
N
C
P
G
A
T
P
E
L
F
K
Y
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513564
217
22842
K202
A
L
S
K
K
G
V
K
S
M
S
L
K
R
S
Chicken
Gallus gallus
XP_414720
437
47503
S415
R
I
T
D
T
G
L
S
Y
L
S
T
M
S
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334619
484
53683
T466
L
T
N
C
P
G
A
T
A
E
L
F
K
Y
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729732
666
71670
S648
L
T
N
C
P
G
A
S
H
E
L
F
D
Y
L
Honey Bee
Apis mellifera
XP_392431
413
45033
Y398
I
T
D
A
A
L
E
Y
I
A
C
D
L
N
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780460
481
52568
S463
V
T
N
C
P
G
A
S
P
K
L
L
Q
Y
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90
96.6
N.A.
96.4
96.6
N.A.
34.4
75.3
N.A.
78.9
N.A.
42
40.5
N.A.
55
Protein Similarity:
100
N.A.
90.6
97.3
N.A.
97.4
97.4
N.A.
37.5
79.7
N.A.
86.5
N.A.
55.2
51.9
N.A.
69.8
P-Site Identity:
100
N.A.
0
100
N.A.
100
100
N.A.
13.3
6.6
N.A.
86.6
N.A.
73.3
6.6
N.A.
66.6
P-Site Similarity:
100
N.A.
0
100
N.A.
100
100
N.A.
20
13.3
N.A.
93.3
N.A.
80
20
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
0
64
10
10
19
0
10
0
10
0
% A
% Cys:
0
0
10
64
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
0
0
0
0
0
10
10
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
0
55
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
55
0
0
46
% F
% Gly:
0
10
0
0
10
82
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
10
% H
% Ile:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
10
0
10
0
10
10
0
55
0
0
% K
% Leu:
55
10
0
0
0
10
10
0
0
10
64
19
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
19
0
0
% M
% Asn:
0
0
64
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
64
0
0
0
46
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% R
% Ser:
0
0
10
0
0
0
0
28
10
0
19
0
0
10
19
% S
% Thr:
0
73
10
0
10
0
0
46
10
0
0
10
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
10
10
0
0
0
0
64
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _