KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXL16
All Species:
26.06
Human Site:
Y129
Identified Species:
57.33
UniProt:
Q8N461
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N461
NP_699181.1
479
51658
Y129
K
A
W
R
R
V
L
Y
Q
P
K
F
W
A
G
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001118521
483
51972
Y129
K
A
W
R
R
V
L
Y
Q
P
K
F
W
A
G
Dog
Lupus familis
XP_547211
483
52133
Y133
K
A
W
R
R
V
L
Y
Q
P
K
F
W
A
G
Cat
Felis silvestris
Mouse
Mus musculus
A2RT62
479
51860
Y129
K
A
W
R
R
V
L
Y
Q
P
K
F
W
A
G
Rat
Rattus norvegicus
Q5MJ12
479
51833
Y129
K
A
W
R
R
V
L
Y
Q
P
K
F
W
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513564
217
22842
Chicken
Gallus gallus
XP_414720
437
47503
S113
S
P
E
R
L
P
G
S
P
S
E
R
Q
L
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001334619
484
53683
Y134
K
T
W
R
K
V
L
Y
Q
P
K
F
W
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729732
666
71670
R318
K
W
R
D
T
L
Y
R
S
P
R
Y
W
S
G
Honey Bee
Apis mellifera
XP_392431
413
45033
P96
G
L
G
N
I
G
T
P
S
R
A
R
I
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780460
481
52568
Y131
K
S
W
K
E
V
L
Y
Q
P
M
F
W
K
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
90
96.6
N.A.
96.4
96.6
N.A.
34.4
75.3
N.A.
78.9
N.A.
42
40.5
N.A.
55
Protein Similarity:
100
N.A.
90.6
97.3
N.A.
97.4
97.4
N.A.
37.5
79.7
N.A.
86.5
N.A.
55.2
51.9
N.A.
69.8
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
6.6
N.A.
80
N.A.
26.6
0
N.A.
60
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
13.3
N.A.
86.6
N.A.
53.3
6.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
46
0
0
0
0
0
0
0
0
10
0
0
46
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
0
10
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
64
0
0
0
% F
% Gly:
10
0
10
0
0
10
10
0
0
0
0
0
0
0
64
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
73
0
0
10
10
0
0
0
0
0
55
0
0
10
0
% K
% Leu:
0
10
0
0
10
10
64
0
0
0
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
10
0
10
10
73
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
64
0
0
0
10
0
0
% Q
% Arg:
0
0
10
64
46
0
0
10
0
10
10
19
0
0
10
% R
% Ser:
10
10
0
0
0
0
0
10
19
10
0
0
0
19
0
% S
% Thr:
0
10
0
0
10
0
10
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
64
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
10
64
0
0
0
0
0
0
0
0
0
73
0
0
% W
% Tyr:
0
0
0
0
0
0
10
64
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _