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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SFRP1
All Species:
25.45
Human Site:
Y249
Identified Species:
56
UniProt:
Q8N474
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N474
NP_003003.3
314
35386
Y249
D
L
K
K
L
V
L
Y
L
K
N
G
A
D
C
Chimpanzee
Pan troglodytes
XP_001138037
314
35311
Y249
D
L
K
K
L
V
L
Y
L
K
N
G
A
D
C
Rhesus Macaque
Macaca mulatta
XP_001094070
314
35256
Y249
D
L
K
K
L
V
L
Y
L
K
N
G
A
D
C
Dog
Lupus familis
XP_849280
393
44150
Y328
E
L
K
K
L
V
L
Y
L
K
N
G
A
D
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8C4U3
314
35309
F249
E
L
K
A
L
V
L
F
L
K
N
G
A
D
C
Rat
Rattus norvegicus
Q9R168
158
18054
K106
K
L
G
P
I
K
K
K
E
L
K
R
L
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506881
184
20608
C132
L
D
R
P
I
Y
P
C
R
W
L
C
K
A
V
Chicken
Gallus gallus
Q9DEQ4
314
35261
L249
N
L
K
K
L
V
L
L
L
K
N
G
A
D
C
Frog
Xenopus laevis
NP_001080957
311
35700
Y246
D
W
A
E
L
V
L
Y
L
K
N
G
A
N
C
Zebra Danio
Brachydanio rerio
NP_571933
310
35375
Y245
D
L
K
K
L
T
L
Y
I
K
N
G
A
N
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781087
422
48633
Y265
D
L
Q
R
L
T
F
Y
V
R
E
G
A
N
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.7
51.6
N.A.
94.9
49
N.A.
49.6
85.3
62.4
65.6
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.3
98.7
57.2
N.A.
96.5
50.3
N.A.
51.5
93.3
79.9
78
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Identity:
100
100
100
93.3
N.A.
80
6.6
N.A.
0
86.6
73.3
80
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
13.3
93.3
86.6
93.3
N.A.
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
0
0
0
0
0
0
82
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
82
% C
% Asp:
55
10
0
0
0
0
0
0
0
0
0
0
0
55
0
% D
% Glu:
19
0
0
10
0
0
0
0
10
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
82
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
19
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
10
0
64
55
0
10
10
10
0
73
10
0
10
0
0
% K
% Leu:
10
82
0
0
82
0
73
10
64
10
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
73
0
0
28
0
% N
% Pro:
0
0
0
19
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
0
0
0
0
10
10
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
64
0
0
10
0
0
0
0
10
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _