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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PNKD All Species: 8.79
Human Site: S43 Identified Species: 17.58
UniProt: Q8N490 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N490 NP_001070867.1 385 42876 S43 N R T R A L Q S H S S P E G K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089254 385 42797 S43 N R T R A L Q S H S S P E G K
Dog Lupus familis XP_853023 430 48112 M43 R T L R G L L M A R S K R L L
Cat Felis silvestris
Mouse Mus musculus Q69ZP3 385 42998 S43 N R T R A L Q S H S S P E C K
Rat Rattus norvegicus O35952 309 34091
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZI23 310 34206
Frog Xenopus laevis NP_001089873 260 29031
Zebra Danio Brachydanio rerio Q6P963 303 33787
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_649258 305 34165
Honey Bee Apis mellifera XP_623458 288 32956
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001184959 268 29968
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O24496 258 28773
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.7 69.5 N.A. 96 34.8 N.A. N.A. 32.7 28 29.6 N.A. 32.4 33.2 N.A. 34.8
Protein Similarity: 100 N.A. 99.7 74.6 N.A. 96.8 46.7 N.A. N.A. 45.9 38.7 44.4 N.A. 49.3 48 N.A. 45.1
P-Site Identity: 100 N.A. 100 20 N.A. 93.3 0 N.A. N.A. 0 0 0 N.A. 0 0 N.A. 0
P-Site Similarity: 100 N.A. 100 20 N.A. 93.3 0 N.A. N.A. 0 0 0 N.A. 0 0 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. 27 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 40.2 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 25 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 0 0 0 0 0 17 0 % G
% His: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 25 % K
% Leu: 0 0 9 0 0 34 9 0 0 0 0 0 0 9 9 % L
% Met: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 25 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 0 % P
% Gln: 0 0 0 0 0 0 25 0 0 0 0 0 0 0 0 % Q
% Arg: 9 25 0 34 0 0 0 0 0 9 0 0 9 0 0 % R
% Ser: 0 0 0 0 0 0 0 25 0 25 34 0 0 0 0 % S
% Thr: 0 9 25 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _