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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM109A
All Species:
29.39
Human Site:
Y115
Identified Species:
58.79
UniProt:
Q8N4B1
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4B1
NP_653272.2
249
27215
Y115
L
S
R
A
S
F
D
Y
L
R
L
V
V
R
E
Chimpanzee
Pan troglodytes
XP_522532
249
27197
Y115
L
S
R
A
S
F
D
Y
L
R
L
V
V
R
E
Rhesus Macaque
Macaca mulatta
XP_001108539
235
25778
Y115
L
S
R
A
S
F
D
Y
L
R
L
V
V
R
E
Dog
Lupus familis
XP_543394
237
25901
Y115
L
S
R
A
S
F
D
Y
L
R
L
V
V
R
E
Cat
Felis silvestris
Mouse
Mus musculus
Q14B98
259
28689
Y123
L
S
R
A
S
F
G
Y
M
R
L
V
V
R
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506251
361
40426
Y115
L
S
R
A
S
F
D
Y
L
R
L
V
V
R
E
Chicken
Gallus gallus
Q5ZLT5
149
17760
R36
K
G
S
V
L
K
K
R
L
V
K
L
V
V
N
Frog
Xenopus laevis
NP_001084930
246
27986
V112
S
F
D
Y
M
R
L
V
V
R
E
L
E
K
Q
Zebra Danio
Brachydanio rerio
Q6P0G8
158
18561
L45
V
K
L
I
V
N
F
L
F
Y
F
R
T
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137795
350
39462
Y112
L
T
C
A
G
Y
E
Y
K
R
I
I
L
A
E
Honey Bee
Apis mellifera
XP_395804
216
25109
Q103
E
S
Q
E
S
M
E
Q
W
M
K
A
L
A
C
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784443
386
43270
Y116
L
S
C
S
S
Y
D
Y
I
K
A
M
V
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91.9
62.2
N.A.
41.3
N.A.
N.A.
45.9
20
40.5
21.6
N.A.
31.4
37.3
N.A.
25.9
Protein Similarity:
100
99.1
93.5
65.8
N.A.
53.2
N.A.
N.A.
52
34.1
53.4
33.7
N.A.
45.1
52.6
N.A.
41.9
P-Site Identity:
100
100
100
100
N.A.
86.6
N.A.
N.A.
100
13.3
6.6
6.6
N.A.
33.3
13.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
N.A.
N.A.
100
20
33.3
13.3
N.A.
73.3
33.3
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
59
0
0
0
0
0
0
9
9
0
17
0
% A
% Cys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
0
0
50
0
0
0
0
0
0
17
0
% D
% Glu:
9
0
0
9
0
0
17
0
0
0
9
0
9
0
75
% E
% Phe:
0
9
0
0
0
50
9
0
9
0
9
0
0
0
0
% F
% Gly:
0
9
0
0
9
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
9
0
9
9
0
0
0
% I
% Lys:
9
9
0
0
0
9
9
0
9
9
17
0
0
9
0
% K
% Leu:
67
0
9
0
9
0
9
9
50
0
50
17
17
0
0
% L
% Met:
0
0
0
0
9
9
0
0
9
9
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
0
0
0
9
0
0
0
0
0
0
9
% Q
% Arg:
0
0
50
0
0
9
0
9
0
67
0
9
0
50
0
% R
% Ser:
9
67
9
9
67
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
9
0
0
9
9
0
0
9
9
9
0
50
67
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
17
0
67
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _