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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM109A
All Species:
19.39
Human Site:
Y231
Identified Species:
38.79
UniProt:
Q8N4B1
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4B1
NP_653272.2
249
27215
Y231
F
A
R
L
H
E
C
Y
G
Q
E
I
R
A
L
Chimpanzee
Pan troglodytes
XP_522532
249
27197
Y231
F
A
R
L
H
E
C
Y
G
Q
E
I
R
A
L
Rhesus Macaque
Macaca mulatta
XP_001108539
235
25778
Y217
F
A
R
L
H
E
C
Y
G
Q
E
I
R
A
L
Dog
Lupus familis
XP_543394
237
25901
C215
G
P
G
P
E
E
P
C
S
R
D
D
A
G
C
Cat
Felis silvestris
Mouse
Mus musculus
Q14B98
259
28689
Y231
F
S
T
L
H
D
W
Y
G
K
E
I
M
E
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506251
361
40426
Y244
F
G
K
L
H
E
W
Y
G
R
E
I
V
E
L
Chicken
Gallus gallus
Q5ZLT5
149
17760
E132
M
T
G
K
D
P
L
E
Q
F
G
I
S
E
E
Frog
Xenopus laevis
NP_001084930
246
27986
Y226
F
S
K
L
H
E
W
Y
G
K
E
V
E
E
L
Zebra Danio
Brachydanio rerio
Q6P0G8
158
18561
R141
Y
G
I
S
D
E
T
R
F
Q
V
N
S
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001137795
350
39462
F328
F
A
R
N
H
E
R
F
R
R
E
L
M
P
D
Honey Bee
Apis mellifera
XP_395804
216
25109
L199
G
R
R
I
L
A
D
L
N
E
W
R
H
T
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784443
386
43270
F366
F
S
D
M
H
E
E
F
G
M
L
I
V
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
91.9
62.2
N.A.
41.3
N.A.
N.A.
45.9
20
40.5
21.6
N.A.
31.4
37.3
N.A.
25.9
Protein Similarity:
100
99.1
93.5
65.8
N.A.
53.2
N.A.
N.A.
52
34.1
53.4
33.7
N.A.
45.1
52.6
N.A.
41.9
P-Site Identity:
100
100
100
6.6
N.A.
53.3
N.A.
N.A.
60
6.6
53.3
26.6
N.A.
40
6.6
N.A.
33.3
P-Site Similarity:
100
100
100
20
N.A.
73.3
N.A.
N.A.
73.3
6.6
80
33.3
N.A.
60
20
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
0
9
0
0
0
0
0
0
9
34
0
% A
% Cys:
0
0
0
0
0
0
25
9
0
0
0
0
0
0
9
% C
% Asp:
0
0
9
0
17
9
9
0
0
0
9
9
0
0
9
% D
% Glu:
0
0
0
0
9
75
9
9
0
9
59
0
9
34
9
% E
% Phe:
67
0
0
0
0
0
0
17
9
9
0
0
0
0
0
% F
% Gly:
17
17
17
0
0
0
0
0
59
0
9
0
0
9
0
% G
% His:
0
0
0
0
67
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
9
9
0
0
0
0
0
0
0
59
0
0
0
% I
% Lys:
0
0
17
9
0
0
0
0
0
17
0
0
0
0
9
% K
% Leu:
0
0
0
50
9
0
9
9
0
0
9
9
0
0
59
% L
% Met:
9
0
0
9
0
0
0
0
0
9
0
0
17
0
0
% M
% Asn:
0
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
9
0
9
0
9
9
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
34
0
0
0
0
0
% Q
% Arg:
0
9
42
0
0
0
9
9
9
25
0
9
25
9
9
% R
% Ser:
0
25
0
9
0
0
0
0
9
0
0
0
17
0
0
% S
% Thr:
0
9
9
0
0
0
9
0
0
0
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
9
17
0
0
% V
% Trp:
0
0
0
0
0
0
25
0
0
0
9
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _