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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FBXO39 All Species: 26.67
Human Site: S353 Identified Species: 83.81
UniProt: Q8N4B4 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4B4 NP_694962.1 442 52646 S353 E F N N N H E S L D E E L H L
Chimpanzee Pan troglodytes XP_001168177 442 52641 S353 E F N N N H E S L D D E L H L
Rhesus Macaque Macaca mulatta XP_001103764 442 52781 S353 E F N N N H E S L D E E L H L
Dog Lupus familis XP_536603 443 52419 S354 E F N N N H E S L D E E L H L
Cat Felis silvestris
Mouse Mus musculus Q5NBU5 443 52535 S354 E F N N N H E S L D E Q L H L
Rat Rattus norvegicus Q66H10 443 52485 S354 E F N N N H E S L D E Q L H L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511725 518 61253 T429 E F N N N H E T L D E E L L Q
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783455 501 57977 L393 D V S P C Y K L Y G R G F I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 93.2 85.3 N.A. 83.7 85.7 N.A. 62.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 21.5
Protein Similarity: 100 99.7 96.8 93.4 N.A. 91.8 92.7 N.A. 72.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 41.7
P-Site Identity: 100 93.3 100 100 N.A. 93.3 93.3 N.A. 80 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 13 0 0 0 0 0 0 0 0 88 13 0 0 0 13 % D
% Glu: 88 0 0 0 0 0 88 0 0 0 75 63 0 0 0 % E
% Phe: 0 88 0 0 0 0 0 0 0 0 0 0 13 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 13 0 13 0 0 0 % G
% His: 0 0 0 0 0 88 0 0 0 0 0 0 0 75 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % I
% Lys: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 13 88 0 0 0 88 13 75 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 88 88 88 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 25 0 0 13 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 13 0 0 0 0 % R
% Ser: 0 0 13 0 0 0 0 75 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % T
% Val: 0 13 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 13 0 0 13 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _