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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO39
All Species:
24.24
Human Site:
T335
Identified Species:
76.19
UniProt:
Q8N4B4
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4B4
NP_694962.1
442
52646
T335
T
L
I
D
L
L
P
T
F
R
H
T
L
Q
K
Chimpanzee
Pan troglodytes
XP_001168177
442
52641
T335
T
L
I
D
L
L
P
T
F
R
H
T
L
Q
K
Rhesus Macaque
Macaca mulatta
XP_001103764
442
52781
T335
T
L
I
D
L
L
P
T
F
R
H
T
L
Q
K
Dog
Lupus familis
XP_536603
443
52419
T336
T
L
T
D
L
L
P
T
F
R
N
T
L
Q
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5NBU5
443
52535
T336
T
L
T
D
L
L
P
T
F
R
N
T
L
Q
K
Rat
Rattus norvegicus
Q66H10
443
52485
T336
T
L
T
D
L
L
P
T
F
R
N
T
L
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511725
518
61253
N411
T
L
T
D
L
L
P
N
Y
R
K
T
L
Q
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783455
501
57977
Y375
T
L
K
Y
V
S
R
Y
L
N
N
T
I
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
93.2
85.3
N.A.
83.7
85.7
N.A.
62.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
21.5
Protein Similarity:
100
99.7
96.8
93.4
N.A.
91.8
92.7
N.A.
72.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
41.7
P-Site Identity:
100
100
100
86.6
N.A.
86.6
86.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
88
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% E
% Phe:
0
0
0
0
0
0
0
0
75
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
38
0
0
0
0
% H
% Ile:
0
0
38
0
0
0
0
0
0
0
0
0
13
0
0
% I
% Lys:
0
0
13
0
0
0
0
0
0
0
13
0
0
0
100
% K
% Leu:
0
100
0
0
88
88
0
0
13
0
0
0
88
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
13
50
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
88
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
88
0
% Q
% Arg:
0
0
0
0
0
0
13
0
0
88
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
13
0
0
0
0
0
0
0
0
0
% S
% Thr:
100
0
50
0
0
0
0
75
0
0
0
100
0
0
0
% T
% Val:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
13
0
0
0
13
13
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _