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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIN All Species: 17.88
Human Site: S1161 Identified Species: 32.78
UniProt: Q8N4C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C6 NP_057434.3 2090 243290 S1161 D L G S T G T S S V Q R Q E V
Chimpanzee Pan troglodytes XP_514559 1391 157093 P585 L P K N R H S P S W S P D G R
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 S1341 D L G S T G T S S V Q R K E V
Dog Lupus familis XP_537442 2129 247435 S1159 D L G S T G T S S A Q R Q E V
Cat Felis silvestris
Mouse Mus musculus Q61043 2035 234755 S1149 D L A S T G T S S V Q R Q E C
Rat Rattus norvegicus NP_001100207 2031 234823 S1154 G L G S T G T S S V Q R Q E C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 R1164 S L E D P E R R K T K S F D E
Chicken Gallus gallus XP_426482 2171 248500 S1222 P C G C G D E S K G E D L D G
Frog Xenopus laevis NP_001086424 1836 213151 K1026 E T E A L L K K H G Y L E E E
Zebra Danio Brachydanio rerio XP_700610 1713 199360 E907 L Q A C L E Q E R E R L Q V D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 L884 L K S T Q S N L E A K S K Q L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 L592 L E E R L A D L E T S K D G V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 L138 K E R F D R A L E S K L L G K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 89 83.1 N.A. 76 76 N.A. 67 55.3 27.1 30.4 N.A. 21.6 N.A. N.A. 22.2
Protein Similarity: 100 42.3 90.6 89.9 N.A. 85.4 85.5 N.A. 79.1 70.1 50 49.8 N.A. 41.4 N.A. N.A. 41.6
P-Site Identity: 100 6.6 93.3 93.3 N.A. 86.6 86.6 N.A. 6.6 13.3 6.6 6.6 N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 20 100 93.3 N.A. 86.6 86.6 N.A. 20 26.6 26.6 13.3 N.A. 33.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 8 8 0 0 16 0 0 0 0 0 % A
% Cys: 0 8 0 16 0 0 0 0 0 0 0 0 0 0 16 % C
% Asp: 31 0 0 8 8 8 8 0 0 0 0 8 16 16 8 % D
% Glu: 8 16 24 0 0 16 8 8 24 8 8 0 8 47 16 % E
% Phe: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % F
% Gly: 8 0 39 0 8 39 0 0 0 16 0 0 0 24 8 % G
% His: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 8 8 0 0 0 8 8 16 0 24 8 16 0 8 % K
% Leu: 31 47 0 0 24 8 0 24 0 0 0 24 16 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 8 0 0 8 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 0 0 8 0 0 8 0 0 0 8 0 0 0 % P
% Gln: 0 8 0 0 8 0 8 0 0 0 39 0 39 8 0 % Q
% Arg: 0 0 8 8 8 8 8 8 8 0 8 39 0 0 8 % R
% Ser: 8 0 8 39 0 8 8 47 47 8 16 16 0 0 0 % S
% Thr: 0 8 0 8 39 0 39 0 0 16 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 31 0 0 0 8 31 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _