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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NIN
All Species:
23.94
Human Site:
S1218
Identified Species:
43.89
UniProt:
Q8N4C6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4C6
NP_057434.3
2090
243290
S1218
C
A
D
C
D
R
A
S
E
K
K
Q
D
L
L
Chimpanzee
Pan troglodytes
XP_514559
1391
157093
N640
T
Q
L
E
T
K
V
N
Y
Y
E
R
E
I
A
Rhesus Macaque
Macaca mulatta
XP_001098065
2270
262399
S1398
C
A
D
C
D
R
A
S
E
K
K
Q
D
L
L
Dog
Lupus familis
XP_537442
2129
247435
S1216
R
A
D
C
S
R
A
S
E
K
K
Q
D
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61043
2035
234755
S1206
R
A
D
C
D
R
A
S
E
R
K
Q
D
L
L
Rat
Rattus norvegicus
NP_001100207
2031
234823
S1211
R
A
D
C
D
R
A
S
E
R
K
R
D
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514688
2127
247037
S1221
H
A
E
C
D
R
T
S
E
E
K
Q
D
L
V
Chicken
Gallus gallus
XP_426482
2171
248500
S1278
G
G
K
M
A
L
E
S
D
C
N
P
D
L
D
Frog
Xenopus laevis
NP_001086424
1836
213151
K1081
S
K
L
Q
L
I
S
K
D
N
E
E
L
E
K
Zebra Danio
Brachydanio rerio
XP_700610
1713
199360
L962
L
S
S
L
L
E
K
L
R
T
D
I
A
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
Q939
D
V
E
S
K
T
K
Q
L
E
A
A
N
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788604
1398
162441
K647
S
E
R
K
V
R
R
K
G
S
K
K
R
G
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
T193
Y
D
T
L
E
E
E
T
D
D
L
K
N
R
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.5
89
83.1
N.A.
76
76
N.A.
67
55.3
27.1
30.4
N.A.
21.6
N.A.
N.A.
22.2
Protein Similarity:
100
42.3
90.6
89.9
N.A.
85.4
85.5
N.A.
79.1
70.1
50
49.8
N.A.
41.4
N.A.
N.A.
41.6
P-Site Identity:
100
0
100
86.6
N.A.
86.6
80
N.A.
66.6
20
0
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
40
100
86.6
N.A.
93.3
93.3
N.A.
86.6
26.6
26.6
6.6
N.A.
20
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
47
0
0
8
0
39
0
0
0
8
8
8
8
16
% A
% Cys:
16
0
0
47
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
8
39
0
39
0
0
0
24
8
8
0
54
0
8
% D
% Glu:
0
8
16
8
8
16
16
0
47
16
16
8
8
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
8
0
0
0
0
0
0
8
0
0
0
0
8
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% I
% Lys:
0
8
8
8
8
8
16
16
0
24
54
16
0
0
8
% K
% Leu:
8
0
16
16
16
8
0
8
8
0
8
0
8
54
47
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
8
8
0
16
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
8
0
0
0
39
0
0
8
% Q
% Arg:
24
0
8
0
0
54
8
0
8
16
0
16
8
8
0
% R
% Ser:
16
8
8
8
8
0
8
54
0
8
0
0
0
0
0
% S
% Thr:
8
0
8
0
8
8
8
8
0
8
0
0
0
0
0
% T
% Val:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _