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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIN All Species: 15.15
Human Site: S1379 Identified Species: 27.78
UniProt: Q8N4C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C6 NP_057434.3 2090 243290 S1379 E C V P R V R S V H H V I E E
Chimpanzee Pan troglodytes XP_514559 1391 157093 A783 E Q L E L E R A L K L Q P C V
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 S1559 E C V P R V R S V H H V I E E
Dog Lupus familis XP_537442 2129 247435 P1374 Q T L D E H V P E V M N V H H
Cat Felis silvestris
Mouse Mus musculus Q61043 2035 234755 S1368 E C T P K V V S M H H I I E E
Rat Rattus norvegicus NP_001100207 2031 234823 S1373 E C T P E V M S R H H I I E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 K1373 K P L E Q M Q K S E P Y G P V
Chicken Gallus gallus XP_426482 2171 248500 S1424 D T L R E L R S F H C E L E G
Frog Xenopus laevis NP_001086424 1836 213151 T1226 Q L E R E T E T S Q D D R M E
Zebra Danio Brachydanio rerio XP_700610 1713 199360 N1105 I E L S R Q L N E L H K Q V Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 I1082 S T G T Q T T I K D L Q E R L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 E790 Q E K E K E S E E D K L S L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 E336 R L K D E L N E L E T K F S E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 89 83.1 N.A. 76 76 N.A. 67 55.3 27.1 30.4 N.A. 21.6 N.A. N.A. 22.2
Protein Similarity: 100 42.3 90.6 89.9 N.A. 85.4 85.5 N.A. 79.1 70.1 50 49.8 N.A. 41.4 N.A. N.A. 41.6
P-Site Identity: 100 13.3 100 0 N.A. 66.6 66.6 N.A. 0 26.6 6.6 13.3 N.A. 0 N.A. N.A. 0
P-Site Similarity: 100 33.3 100 20 N.A. 86.6 73.3 N.A. 33.3 53.3 20 33.3 N.A. 6.6 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % A
% Cys: 0 31 0 0 0 0 0 0 0 0 8 0 0 8 0 % C
% Asp: 8 0 0 16 0 0 0 0 0 16 8 8 0 0 0 % D
% Glu: 39 16 8 24 39 16 8 16 24 16 0 8 8 39 47 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 8 % G
% His: 0 0 0 0 0 8 0 0 0 39 39 0 0 8 8 % H
% Ile: 8 0 0 0 0 0 0 8 0 0 0 16 31 0 0 % I
% Lys: 8 0 16 0 16 0 0 8 8 8 8 16 0 0 0 % K
% Leu: 0 16 39 0 8 16 8 0 16 8 16 8 8 8 8 % L
% Met: 0 0 0 0 0 8 8 0 8 0 8 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 8 8 0 0 0 8 0 0 0 % N
% Pro: 0 8 0 31 0 0 0 8 0 0 8 0 8 8 0 % P
% Gln: 24 8 0 0 16 8 8 0 0 8 0 16 8 0 8 % Q
% Arg: 8 0 0 16 24 0 31 0 8 0 0 0 8 8 0 % R
% Ser: 8 0 0 8 0 0 8 39 16 0 0 0 8 8 0 % S
% Thr: 0 24 16 8 0 16 8 8 0 0 8 0 0 0 0 % T
% Val: 0 0 16 0 0 31 16 0 16 8 0 16 8 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _