KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NIN
All Species:
24.85
Human Site:
S1538
Identified Species:
45.56
UniProt:
Q8N4C6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4C6
NP_057434.3
2090
243290
S1538
T
T
L
N
E
E
D
S
I
S
N
L
K
L
G
Chimpanzee
Pan troglodytes
XP_514559
1391
157093
E935
G
A
S
A
A
G
L
E
Q
P
G
A
R
E
L
Rhesus Macaque
Macaca mulatta
XP_001098065
2270
262399
S1719
T
T
L
N
E
E
D
S
I
S
N
L
K
L
G
Dog
Lupus familis
XP_537442
2129
247435
S1533
T
T
L
N
E
E
D
S
I
S
N
L
K
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61043
2035
234755
S1528
T
T
L
N
E
E
D
S
I
S
N
L
K
L
E
Rat
Rattus norvegicus
NP_001100207
2031
234823
S1533
T
T
L
N
E
E
D
S
I
S
N
L
K
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514688
2127
247037
S1531
T
S
L
N
E
D
G
S
I
S
N
L
K
L
R
Chicken
Gallus gallus
XP_426482
2171
248500
S1585
T
L
L
N
E
E
G
S
A
S
S
L
R
L
R
Frog
Xenopus laevis
NP_001086424
1836
213151
Q1379
D
Q
L
E
K
D
L
Q
R
F
K
D
E
N
Q
Zebra Danio
Brachydanio rerio
XP_700610
1713
199360
A1257
C
P
E
S
I
D
K
A
I
P
V
H
I
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
K1234
Q
E
L
Q
D
S
V
K
Q
K
E
E
L
V
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788604
1398
162441
E942
G
L
K
G
Q
L
K
E
D
F
I
D
L
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32380
944
111763
K488
D
L
K
V
A
Q
E
K
Y
S
K
M
E
K
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.5
89
83.1
N.A.
76
76
N.A.
67
55.3
27.1
30.4
N.A.
21.6
N.A.
N.A.
22.2
Protein Similarity:
100
42.3
90.6
89.9
N.A.
85.4
85.5
N.A.
79.1
70.1
50
49.8
N.A.
41.4
N.A.
N.A.
41.6
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
73.3
60
6.6
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
86.6
73.3
26.6
33.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
16
0
0
8
8
0
0
8
0
0
0
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
0
8
24
39
0
8
0
0
16
0
0
8
% D
% Glu:
0
8
8
8
54
47
8
16
0
0
8
8
16
8
24
% E
% Phe:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% F
% Gly:
16
0
0
8
0
8
16
0
0
0
8
0
0
0
24
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
54
0
8
0
8
8
0
% I
% Lys:
0
0
16
0
8
0
16
16
0
8
16
0
47
8
0
% K
% Leu:
0
24
70
0
0
8
16
0
0
0
0
54
16
62
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
54
0
0
0
0
0
0
47
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
0
0
0
16
0
0
0
0
0
% P
% Gln:
8
8
0
8
8
8
0
8
16
0
0
0
0
0
16
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
16
0
16
% R
% Ser:
0
8
8
8
0
8
0
54
0
62
8
0
0
0
8
% S
% Thr:
54
39
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
8
0
0
8
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _