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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIN All Species: 26.97
Human Site: S1652 Identified Species: 49.44
UniProt: Q8N4C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C6 NP_057434.3 2090 243290 S1652 E R C K V Q S S T L V S S L E
Chimpanzee Pan troglodytes XP_514559 1391 157093 W1036 V A D P Q G S W Q E Q L A A P
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 S1833 E R C K V Q S S T L V S S L E
Dog Lupus familis XP_537442 2129 247435 S1647 E Q C K A Q S S A L V S S L E
Cat Felis silvestris
Mouse Mus musculus Q61043 2035 234755 S1641 D H Y K V Q T S T L V S S L E
Rat Rattus norvegicus NP_001100207 2031 234823 S1646 D R Y K V Q T S T L V S S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 S1645 E D C K V K S S A L V S S L E
Chicken Gallus gallus XP_426482 2171 248500 S1699 E S N K A K S S N V V S S L E
Frog Xenopus laevis NP_001086424 1836 213151 N1480 R E E L R Q L N T Q S L Q L S
Zebra Danio Brachydanio rerio XP_700610 1713 199360 K1358 S S E L K N L K T N S R E T Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 T1335 E E K L Q A A T S Q L D A Q Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 E1043 M A D K H R K E I D D L M R M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 S589 A E N S A K V S E K R S K D I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 89 83.1 N.A. 76 76 N.A. 67 55.3 27.1 30.4 N.A. 21.6 N.A. N.A. 22.2
Protein Similarity: 100 42.3 90.6 89.9 N.A. 85.4 85.5 N.A. 79.1 70.1 50 49.8 N.A. 41.4 N.A. N.A. 41.6
P-Site Identity: 100 6.6 100 80 N.A. 73.3 80 N.A. 80 60 20 6.6 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 86.6 N.A. 86.6 93.3 N.A. 86.6 73.3 26.6 13.3 N.A. 46.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 16 0 0 24 8 8 0 16 0 0 0 16 8 0 % A
% Cys: 0 0 31 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 8 16 0 0 0 0 0 0 8 8 8 0 8 0 % D
% Glu: 47 24 16 0 0 0 0 8 8 8 0 0 8 0 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % G
% His: 0 8 0 0 8 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 8 % I
% Lys: 0 0 8 62 8 24 8 8 0 8 0 0 8 0 0 % K
% Leu: 0 0 0 24 0 0 16 0 0 47 8 24 0 62 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % M
% Asn: 0 0 16 0 0 8 0 8 8 8 0 0 0 0 0 % N
% Pro: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 8 % P
% Gln: 0 8 0 0 16 47 0 0 8 16 8 0 8 8 16 % Q
% Arg: 8 24 0 0 8 8 0 0 0 0 8 8 0 8 0 % R
% Ser: 8 16 0 8 0 0 47 62 8 0 16 62 54 0 8 % S
% Thr: 0 0 0 0 0 0 16 8 47 0 0 0 0 8 0 % T
% Val: 8 0 0 0 39 0 8 0 0 8 54 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _