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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIN All Species: 23.64
Human Site: S1754 Identified Species: 43.33
UniProt: Q8N4C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C6 NP_057434.3 2090 243290 S1754 Q K S W E H Q S A S L K S Q L
Chimpanzee Pan troglodytes XP_514559 1391 157093 K1126 R K E I E V L K K D K E K A C
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 S1935 Q K S W E H E S A S L K S Q L
Dog Lupus familis XP_537442 2129 247435 S1749 Q K S W E H Q S E T L K S Q L
Cat Felis silvestris
Mouse Mus musculus Q61043 2035 234755 S1743 Q T A W E E Q S E S L K S Q L
Rat Rattus norvegicus NP_001100207 2031 234823 S1748 R E A W E E Q S Q D L K S Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 S1747 Q K T W E Q Q S E T L K L Q L
Chicken Gallus gallus XP_426482 2171 248500 S1801 Q K S W E Q Q S Q T L K A Q L
Frog Xenopus laevis NP_001086424 1836 213151 H1571 M E N H T Q K H M R E K E G L
Zebra Danio Brachydanio rerio XP_700610 1713 199360 D1448 N E E D R V A D L R D V C L Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 A1425 I Q D K L E Q A Q Q K E R T L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 V1133 M M E M A V R V E V Q R N V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 R679 I E I E N W K R K Y N N L S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 89 83.1 N.A. 76 76 N.A. 67 55.3 27.1 30.4 N.A. 21.6 N.A. N.A. 22.2
Protein Similarity: 100 42.3 90.6 89.9 N.A. 85.4 85.5 N.A. 79.1 70.1 50 49.8 N.A. 41.4 N.A. N.A. 41.6
P-Site Identity: 100 13.3 93.3 86.6 N.A. 73.3 60 N.A. 66.6 73.3 13.3 0 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 26.6 100 93.3 N.A. 80 80 N.A. 80 86.6 33.3 6.6 N.A. 33.3 N.A. N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 0 8 0 8 8 16 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % C
% Asp: 0 0 8 8 0 0 0 8 0 16 8 0 0 0 0 % D
% Glu: 0 31 24 8 62 24 8 0 31 0 8 16 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % G
% His: 0 0 0 8 0 24 0 8 0 0 0 0 0 0 0 % H
% Ile: 16 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 47 0 8 0 0 16 8 16 0 16 62 8 0 0 % K
% Leu: 0 0 0 0 8 0 8 0 8 0 54 0 16 8 77 % L
% Met: 16 8 0 8 0 0 0 0 8 0 0 0 0 0 0 % M
% Asn: 8 0 8 0 8 0 0 0 0 0 8 8 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 47 8 0 0 0 24 54 0 24 8 8 0 0 54 8 % Q
% Arg: 16 0 0 0 8 0 8 8 0 16 0 8 8 0 0 % R
% Ser: 0 0 31 0 0 0 0 54 0 24 0 0 39 8 0 % S
% Thr: 0 8 8 0 8 0 0 0 0 24 0 0 0 8 0 % T
% Val: 0 0 0 0 0 24 0 8 0 8 0 8 0 8 0 % V
% Trp: 0 0 0 54 0 8 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _