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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIN All Species: 28.79
Human Site: S398 Identified Species: 52.78
UniProt: Q8N4C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C6 NP_057434.3 2090 243290 S398 D K A E K L K S L M A S E V D
Chimpanzee Pan troglodytes XP_514559 1391 157093
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 S579 D K A E K L K S L M A S E V D
Dog Lupus familis XP_537442 2129 247435 S395 D K A E K L K S L M A S E V D
Cat Felis silvestris
Mouse Mus musculus Q61043 2035 234755 S398 D K A E K L K S L M A S E V D
Rat Rattus norvegicus NP_001100207 2031 234823 S398 D K A E K L K S L M A S E V D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 S398 E K A E R L K S L M A S E V D
Chicken Gallus gallus XP_426482 2171 248500 S488 E K A E K L K S L M A S E V D
Frog Xenopus laevis NP_001086424 1836 213151 D358 G E R V N L L D L T T A L D N
Zebra Danio Brachydanio rerio XP_700610 1713 199360 S242 M D V Q E F I S C V I N H S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 A219 S R T V S P T A S I R S S M L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 89 83.1 N.A. 76 76 N.A. 67 55.3 27.1 30.4 N.A. 21.6 N.A. N.A. 22.2
Protein Similarity: 100 42.3 90.6 89.9 N.A. 85.4 85.5 N.A. 79.1 70.1 50 49.8 N.A. 41.4 N.A. N.A. 41.6
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 86.6 93.3 13.3 6.6 N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 100 100 33.3 33.3 N.A. 33.3 N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 54 0 0 0 0 8 0 0 54 8 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 39 8 0 0 0 0 0 8 0 0 0 0 0 8 54 % D
% Glu: 16 8 0 54 8 0 0 0 0 0 0 0 54 0 0 % E
% Phe: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 8 8 0 0 0 0 % I
% Lys: 0 54 0 0 47 0 54 0 0 0 0 0 0 0 8 % K
% Leu: 0 0 0 0 0 62 8 0 62 0 0 0 8 0 8 % L
% Met: 8 0 0 0 0 0 0 0 0 54 0 0 0 8 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 0 0 8 0 0 8 % N
% Pro: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 8 0 8 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 8 0 0 0 8 0 0 62 8 0 0 62 8 8 0 % S
% Thr: 0 0 8 0 0 0 8 0 0 8 8 0 0 0 0 % T
% Val: 0 0 8 16 0 0 0 0 0 8 0 0 0 54 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _