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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIN All Species: 13.94
Human Site: T1966 Identified Species: 25.56
UniProt: Q8N4C6 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C6 NP_057434.3 2090 243290 T1966 E M Q H L R S T A T P S P S P
Chimpanzee Pan troglodytes XP_514559 1391 157093 L1317 I L K N M E M L L Q E K V D K
Rhesus Macaque Macaca mulatta XP_001098065 2270 262399 T2146 E M Q H L R F T A T P S P S P
Dog Lupus familis XP_537442 2129 247435 T1962 E M Q H L R S T A M L S P S P
Cat Felis silvestris
Mouse Mus musculus Q61043 2035 234755 T1956 E M Q P L R S T V T R S P S S
Rat Rattus norvegicus NP_001100207 2031 234823 A1952 Q M Q P L R S A G T H S P S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514688 2127 247037 G1960 E M Q P S R S G V T L S P P Q
Chicken Gallus gallus XP_426482 2171 248500 S2007 E M R H S S G S G M L S Q P L
Frog Xenopus laevis NP_001086424 1836 213151 M1762 D L K N V R L M L Q E K V N Q
Zebra Danio Brachydanio rerio XP_700610 1713 199360 S1639 R A L A D L Q S K S F R I H T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VJE5 1690 189046 R1616 A F D A L T K R K P A P R L F
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_788604 1398 162441 R1324 E K K Y R K M R A M L E E Y M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32380 944 111763 N870 E L D R D Y Y N S H V Y T R Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.5 89 83.1 N.A. 76 76 N.A. 67 55.3 27.1 30.4 N.A. 21.6 N.A. N.A. 22.2
Protein Similarity: 100 42.3 90.6 89.9 N.A. 85.4 85.5 N.A. 79.1 70.1 50 49.8 N.A. 41.4 N.A. N.A. 41.6
P-Site Identity: 100 0 93.3 86.6 N.A. 73.3 60 N.A. 53.3 26.6 6.6 0 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 26.6 93.3 86.6 N.A. 73.3 66.6 N.A. 53.3 40 46.6 13.3 N.A. 6.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 0 16 0 0 0 8 31 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 16 0 16 0 0 0 0 0 0 0 0 8 0 % D
% Glu: 62 0 0 0 0 8 0 0 0 0 16 8 8 0 0 % E
% Phe: 0 8 0 0 0 0 8 0 0 0 8 0 0 0 8 % F
% Gly: 0 0 0 0 0 0 8 8 16 0 0 0 0 0 0 % G
% His: 0 0 0 31 0 0 0 0 0 8 8 0 0 8 0 % H
% Ile: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 8 24 0 0 8 8 0 16 0 0 16 0 0 8 % K
% Leu: 0 24 8 0 47 8 8 8 16 0 31 0 0 8 8 % L
% Met: 0 54 0 0 8 0 16 8 0 24 0 0 0 0 8 % M
% Asn: 0 0 0 16 0 0 0 8 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 24 0 0 0 0 0 8 16 8 47 16 24 % P
% Gln: 8 0 47 0 0 0 8 0 0 16 0 0 8 0 16 % Q
% Arg: 8 0 8 8 8 54 0 16 0 0 8 8 8 8 0 % R
% Ser: 0 0 0 0 16 8 39 16 8 8 0 54 0 39 16 % S
% Thr: 0 0 0 0 0 8 0 31 0 39 0 0 8 0 8 % T
% Val: 0 0 0 0 8 0 0 0 16 0 8 0 16 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 0 8 8 0 0 0 0 8 0 8 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _