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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: STX19 All Species: 34.24
Human Site: S86 Identified Species: 62.78
UniProt: Q8N4C7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4C7 NP_001001850.1 294 34324 S86 V A S M R R F S L L K R E S T
Chimpanzee Pan troglodytes XP_001137843 294 34328 S86 V A S M R R F S L L K R E S T
Rhesus Macaque Macaca mulatta XP_001087826 287 33195 S81 T S M R R L S S I K R D T N S
Dog Lupus familis XP_545055 294 34240 S86 L A S M R R F S L L K R E S S
Cat Felis silvestris
Mouse Mus musculus Q8R1Q0 292 33848 S84 V A S M R R F S L L K R D S T
Rat Rattus norvegicus Q08849 289 33239 E83 D L E Q L T T E I K K R A N N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521876 293 34382 S87 V A S M R R F S V L K K E S S
Chicken Gallus gallus XP_001233073 291 34219 S85 V S S M R R F S V L K K E S N
Frog Xenopus laevis NP_001088058 292 34013 S86 V S S M R R F S V M K R E D N
Zebra Danio Brachydanio rerio XP_698933 296 34714 S90 V A T M R R L S I M K K E S N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24547 291 33630 N88 L M A D I K K N A N R V R G K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O16000 291 33234 A87 L M A V I K R A A N K V R G K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32867 290 33088 T88 D N F V A Q A T D L Q F K L K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 37.7 90.8 N.A. 86 30.9 N.A. 78.5 62.9 62.9 51 N.A. 27.5 N.A. 29.9 N.A.
Protein Similarity: 100 100 62.2 94.5 N.A. 92.8 53 N.A. 90.4 80.6 79.5 71.9 N.A. 48.6 N.A. 52 N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 93.3 13.3 N.A. 80 73.3 66.6 60 N.A. 0 N.A. 6.6 N.A.
P-Site Similarity: 100 100 46.6 100 N.A. 100 26.6 N.A. 100 93.3 86.6 86.6 N.A. 33.3 N.A. 40 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.7 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 47 16 0 8 0 8 8 16 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 16 0 0 8 0 0 0 0 8 0 0 8 8 8 0 % D
% Glu: 0 0 8 0 0 0 0 8 0 0 0 0 54 0 0 % E
% Phe: 0 0 8 0 0 0 54 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 16 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 16 0 0 0 24 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 16 8 0 0 16 77 24 8 0 24 % K
% Leu: 24 8 0 0 8 8 8 0 31 54 0 0 0 8 0 % L
% Met: 0 16 8 62 0 0 0 0 0 16 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 8 0 16 0 0 0 16 31 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 8 0 8 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 0 8 70 62 8 0 0 0 16 47 16 0 0 % R
% Ser: 0 24 54 0 0 0 8 70 0 0 0 0 0 54 24 % S
% Thr: 8 0 8 0 0 8 8 8 0 0 0 0 8 0 24 % T
% Val: 54 0 0 16 0 0 0 0 24 0 0 16 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _