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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX19
All Species:
8.79
Human Site:
T25
Identified Species:
16.11
UniProt:
Q8N4C7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4C7
NP_001001850.1
294
34324
T25
S
R
D
S
H
V
S
T
T
E
T
E
E
Q
G
Chimpanzee
Pan troglodytes
XP_001137843
294
34328
T25
S
R
D
S
H
V
S
T
T
E
T
E
E
Q
G
Rhesus Macaque
Macaca mulatta
XP_001087826
287
33195
E25
Q
F
P
D
G
D
D
E
F
D
S
P
H
E
D
Dog
Lupus familis
XP_545055
294
34240
A25
S
K
D
R
H
V
S
A
I
E
A
E
E
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Q0
292
33848
V23
E
L
S
R
D
G
Q
V
F
V
E
E
E
Q
G
Rat
Rattus norvegicus
Q08849
289
33239
N28
E
V
E
I
A
I
D
N
T
A
F
M
D
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521876
293
34382
S26
R
V
N
S
C
I
A
S
V
G
A
E
E
Q
G
Chicken
Gallus gallus
XP_001233073
291
34219
P25
A
G
E
N
N
C
P
P
V
Q
D
E
Q
E
E
Frog
Xenopus laevis
NP_001088058
292
34013
L25
C
K
E
T
E
S
S
L
V
D
Q
K
E
P
D
Zebra Danio
Brachydanio rerio
XP_698933
296
34714
D29
K
P
F
N
K
E
E
D
E
D
M
D
P
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Y32
N
V
D
G
H
D
S
Y
M
D
D
F
F
A
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
M32
D
T
G
N
A
Q
Y
M
E
E
F
F
E
Q
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32867
290
33088
E29
G
S
S
A
I
G
A
E
G
H
D
F
V
G
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
37.7
90.8
N.A.
86
30.9
N.A.
78.5
62.9
62.9
51
N.A.
27.5
N.A.
29.9
N.A.
Protein Similarity:
100
100
62.2
94.5
N.A.
92.8
53
N.A.
90.4
80.6
79.5
71.9
N.A.
48.6
N.A.
52
N.A.
P-Site Identity:
100
100
0
66.6
N.A.
26.6
6.6
N.A.
33.3
6.6
13.3
0
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
100
20
73.3
N.A.
26.6
33.3
N.A.
60
53.3
46.6
20
N.A.
33.3
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
16
0
16
8
0
8
16
0
0
8
0
% A
% Cys:
8
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
31
8
8
16
16
8
0
31
24
8
8
0
16
% D
% Glu:
16
0
24
0
8
8
8
16
16
31
8
47
54
24
8
% E
% Phe:
0
8
8
0
0
0
0
0
16
0
16
24
8
0
16
% F
% Gly:
8
8
8
8
8
16
0
0
8
8
0
0
0
8
39
% G
% His:
0
0
0
0
31
0
0
0
0
8
0
0
8
0
0
% H
% Ile:
0
0
0
8
8
16
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
16
0
0
8
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
8
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
8
8
0
0
0
% M
% Asn:
8
0
8
24
8
0
0
8
0
0
0
0
0
0
0
% N
% Pro:
0
8
8
0
0
0
8
8
0
0
0
8
8
8
0
% P
% Gln:
8
0
0
0
0
8
8
0
0
8
8
0
8
47
8
% Q
% Arg:
8
16
0
16
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
24
8
16
24
0
8
39
8
0
0
8
0
0
8
8
% S
% Thr:
0
8
0
8
0
0
0
16
24
0
16
0
0
0
0
% T
% Val:
0
24
0
0
0
24
0
8
24
8
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _