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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX19
All Species:
39.7
Human Site:
Y274
Identified Species:
72.78
UniProt:
Q8N4C7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4C7
NP_001001850.1
294
34324
Y274
K
F
G
L
A
V
K
Y
K
K
R
N
P
C
R
Chimpanzee
Pan troglodytes
XP_001137843
294
34328
Y274
K
F
G
L
A
V
K
Y
K
K
R
N
P
C
R
Rhesus Macaque
Macaca mulatta
XP_001087826
287
33195
Y269
Q
V
R
K
A
V
Q
Y
K
K
K
N
P
C
R
Dog
Lupus familis
XP_545055
294
34240
Y274
K
F
G
L
A
V
K
Y
K
K
R
N
P
C
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1Q0
292
33848
Y272
K
F
G
L
A
V
K
Y
K
K
R
N
P
C
R
Rat
Rattus norvegicus
Q08849
289
33239
Y256
E
T
K
R
A
M
K
Y
Q
G
Q
A
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521876
293
34382
Y275
K
F
R
L
A
V
R
Y
K
K
R
N
P
C
R
Chicken
Gallus gallus
XP_001233073
291
34219
Y273
K
F
G
L
A
V
R
Y
R
K
R
H
P
C
K
Frog
Xenopus laevis
NP_001088058
292
34013
Y274
K
F
K
L
A
A
K
Y
K
R
K
N
P
C
R
Zebra Danio
Brachydanio rerio
XP_698933
296
34714
Y278
K
F
K
R
A
A
R
Y
K
K
N
N
P
L
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Y260
D
T
K
K
A
L
K
Y
Q
S
K
A
R
R
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
O16000
291
33234
Y258
D
T
K
K
A
V
Q
Y
Q
S
K
A
R
R
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32867
290
33088
C266
A
R
K
N
K
I
R
C
W
L
I
V
F
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
37.7
90.8
N.A.
86
30.9
N.A.
78.5
62.9
62.9
51
N.A.
27.5
N.A.
29.9
N.A.
Protein Similarity:
100
100
62.2
94.5
N.A.
92.8
53
N.A.
90.4
80.6
79.5
71.9
N.A.
48.6
N.A.
52
N.A.
P-Site Identity:
100
100
60
93.3
N.A.
100
20
N.A.
86.6
73.3
73.3
60
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
100
80
100
N.A.
100
53.3
N.A.
93.3
100
86.6
66.6
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
93
16
0
0
0
0
0
24
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
62
0
% C
% Asp:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
62
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
39
0
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
8
0
0
0
8
% I
% Lys:
62
0
47
24
8
0
54
0
62
62
31
0
0
8
39
% K
% Leu:
0
0
0
54
0
8
0
0
0
8
0
0
0
8
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
8
62
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
70
0
0
% P
% Gln:
8
0
0
0
0
0
16
0
24
0
8
0
0
0
0
% Q
% Arg:
0
8
16
16
0
0
31
0
8
8
47
0
24
16
54
% R
% Ser:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% S
% Thr:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
8
0
0
0
62
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
93
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _