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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDCL2 All Species: 19.39
Human Site: S231 Identified Species: 35.56
UniProt: Q8N4E4 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N4E4 NP_689614.2 241 28071 S231 N T S I H D D S D S S N S D N
Chimpanzee Pan troglodytes XP_526622 241 28036 S231 N T S I H D D S D S S N S D N
Rhesus Macaque Macaca mulatta XP_001087954 241 27921 S231 N T S I H D D S D S S N S D N
Dog Lupus familis XP_532378 335 37869 T324 N T S I Y D D T N S S N S D N
Cat Felis silvestris
Mouse Mus musculus Q78Y63 240 27751 D231 N I S I Y D S D S S G S D T E
Rat Rattus norvegicus Q4KLJ8 240 27681 R226 D V L L S S V R D P V P M R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520868 256 30002 S238 N T S I Y D D S N S S S S E D
Chicken Gallus gallus XP_420702 244 28537 M231 N I S V H E N M D T K S S D V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q6P268 239 27638 R230 R C S A N T H R D G E E D S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MR62 240 27421 M228 R P Q I R D K M L A D L E D K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794769 241 27321 Q230 N I F S G R N Q N V D D S D D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64628 211 24432 S185 V I H Y D G E S S S L K P K S
Baker's Yeast Sacchar. cerevisiae Q12017 286 32775 D273 N V G I G G N D D G N I N D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 97 65.9 N.A. 87.1 56 N.A. 76.5 72.5 N.A. 55.5 N.A. 40.2 N.A. N.A. 44.8
Protein Similarity: 100 99.5 99.5 70.4 N.A. 95.8 75.5 N.A. 89.4 87.3 N.A. 74.2 N.A. 66.3 N.A. N.A. 69.7
P-Site Identity: 100 100 100 80 N.A. 33.3 6.6 N.A. 66.6 40 N.A. 13.3 N.A. 20 N.A. N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 46.6 20 N.A. 100 73.3 N.A. 26.6 N.A. 26.6 N.A. N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. 24.9 29.3 N.A.
Protein Similarity: N.A. N.A. N.A. 47.7 47.5 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 8 0 0 0 0 0 % A
% Cys: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 0 8 54 39 16 54 0 16 8 16 62 31 % D
% Glu: 0 0 0 0 0 8 8 0 0 0 8 8 8 8 8 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 8 0 16 16 0 0 0 16 8 0 0 0 0 % G
% His: 0 0 8 0 31 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 31 0 62 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 8 8 0 8 8 % K
% Leu: 0 0 8 8 0 0 0 0 8 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 16 0 0 0 0 8 0 0 % M
% Asn: 70 0 0 0 8 0 24 0 24 0 8 31 8 0 31 % N
% Pro: 0 8 0 0 0 0 0 0 0 8 0 8 8 0 0 % P
% Gln: 0 0 8 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 16 0 0 0 8 8 0 16 0 0 0 0 0 8 8 % R
% Ser: 0 0 62 8 8 8 8 39 16 54 39 24 54 8 8 % S
% Thr: 0 39 0 0 0 8 0 8 0 8 0 0 0 8 0 % T
% Val: 8 16 0 8 0 0 8 0 0 8 8 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 24 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _